54-31-9|FurosemideProducts Supply - Chemical intermediates Network

Furosemide cas no:54-31-9

Synonyms: 5-(aminosulfonyl)-4-chloro-2-((2-furanylmethyl)amino)benzoic acid; 4-chloro-n-furfuryl-5-sulfamoylanthranilic acid; 2-furfurylamino-4-chloro-5-sulfamoylbenzoic acid

Identification

NameFurosemide
CAS54-31-9
Synonyms5-(aminosulfonyl)-4-chloro-2-((2-furanylmethyl)amino)benzoic acid; 4-chloro-n-furfuryl-5-sulfamoylanthranilic acid; 2-furfurylamino-4-chloro-5-sulfamoylbenzoic acid
EINECS(EC#)200-203-6
Molecular FormulaC12H11ClN2O5S
Molecular Weight330.74414

Chemical Properties

Appearancewhite powder
storage temp2-8°C

Safety Data

Hazard T:Toxic;
Risk R61
Safety

Hazard Codes of Furosemide (CAS NO.54-31-9): TF
Risk Statements: 61-39/23/24/25-11
61: May cause harm to the unborn child
39/23/24/25: Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed
11: Highly Flammable
Safety Statements: 7-16-45-53-36/37/39-22
7: Keep container tightly closed
16: Keep away from sources of ignition - No smoking
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
53: Avoid exposure - obtain special instruction before use
36/37/39: Wear suitable protective clothing, gloves and eye/face protection
22: Do not breathe dust
RIDADR: UN 1230 3/PG 2
WGK Germany: 3
RTECS: CB2625000

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	> 400mg/kg (400mg/kg)		Drugs in Japan Vol. 6, Pg. 725, 1982.
dog	LD50	oral	2gm/kg (2000mg/kg)		Drugs in Japan Vol. 6, Pg. 725, 1982.
human	TDLo	intravenous	1300ug/kg (1.3mg/kg)	CARDIAC: OTHER CHANGES VASCULAR: REGIONAL OR GENERAL ARTERIOLAR CONSTRICTION	Annals of Internal Medicine. Vol. 103, Pg. 1, 1985.
infant	TDLo	intravenous	1mg/kg/4H-I (1mg/kg)		Archives of Disease in Childhood. Vol. 59, Pg. 907, 1984.
man	TDLo	intravenous	29mg/kg (29mg/kg)	SENSE ORGANS AND SPECIAL SENSES: CHANGE IN ACUITY: EAR SENSE ORGANS AND SPECIAL SENSES: TINNITUS: EAR KIDNEY, URETER, AND BLADDER: URINE VOLUME DECREASED	New England Journal of Medicine. Vol. 282, Pg. 1413, 1970.
mouse	LD50	intravenous	308mg/kg (308mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 14, Pg. 44, 1964.
mouse	LD50	oral	2gm/kg (2000mg/kg)		European Patent Application. Vol. #0008367,
mouse	LD50	unreported	900mg/kg (900mg/kg)		European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 15, Pg. 386, 1980.
rabbit	LD50	intravenous	400mg/kg (400mg/kg)		Drugs in Japan Vol. 6, Pg. 725, 1982.
rabbit	LD50	oral	800mg/kg (800mg/kg)		Drugs in Japan Vol. 6, Pg. 725, 1982.
rat	LD50	intraperitoneal	800mg/kg (800mg/kg)		Acta Poloniae Pharmaceutica. For English translation, see APPFAR. Vol. 42, Pg. 199, 1985.
rat	LD50	intravenous	800mg/kg (800mg/kg)		Drugs in Japan Vol. 6, Pg. 725, 1982.
rat	LD50	oral	2600mg/kg (2600mg/kg)		Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971.
rat	LD50	subcutaneous	4600mg/kg (4600mg/kg)		Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 9, Pg. 759, 1967.
women	TDLo	intravenous	2500ug/kg/2M- (2.5mg/kg)	CARDIAC: PULSE RATE	Intensive Care Medicine. Vol. 12, Pg. 54, 1986.
women	TDLo	oral	6250ug/kg (6.25mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS	Journal of Toxicology, Clinical Toxicology. Vol. 31, Pg. 341, 1993.
women	TDLo	oral	120mg/kg/21W- (120mg/kg)	KIDNEY, URETER, AND BLADDER: INTERSTITIAL NEPHRITIS	Journal of the Royal Society of Medicine. Vol. 79, Pg. 239, 1986.

supplier list

Saniver Limited: Tel:; Address: 805 Harbour Centre, Tower 2, 8 Hok Cheung St., Hunghom, Kowloon, Hong Kong.

Hangzhou Starshine Pharmaceutical Co., LTD: Tel:86-571-8696517; Address: Fengqi East Road, Hangzhou, China.

SHENYANG CHENGTAI FINE CHEMICALS FACTORY: Tel:+971-7-2461461; Address: RAK Air port road,RAK

Maxpharm Group: Tel:; Address: B-24AB, Qingnian Plaza, Wuhan, 430022, China

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Datang (Hangzhou) Pharmachem Co., Ltd.: Tel:; Address: Block B, 5F, Huanglong Hengli Mansion,No.5 Huanglong Road,310007, Hangzhou, China

Zhejiang HuTu PharmChem Co., Ltd.: Tel:+86-570-6121003 +86-570-6121498; Address: 2 Yuanyi Road, Kaihua Industrial Park, Zhejiang, China

K.-W.Pfannenschmidt GmbH: Tel:; Address:

Unispec Chemicals Co.ltd: Tel:; Address: B2302 Technology Building, No.5 New Model Road, Nanjing, China P.C

Song's PharmChem Inc.: Tel:+86-(21)-6612-5360; Address:

Leawell International Limited: Tel:+852-(2576)-0298; Address: 18/F Catic Plaza, 8 Causeway Road Causeway Bay,

Praevideo LLC: Tel:+36-(1)-347-0332; Address: Baross U. 46, Budapest H 1192,

Shon Products: Tel:; Address: Plot No. 17-A, Sattur Industrial Estate, Dharwad, Andhra Pradesh 580002,

Ningbo Pangs Chem Int'l Co. Ltd.: Tel:+86-(574)-27668808; Address: Floor 21, Building 11, Xintiandi, No. 689, Shiji Road, Ningbo 315040,

Sonachi Industries Ltd.: Tel:+91-(22)-66929981, 66929982; Address: A/38, 2 nd Floor, Raj Industrial Complex, Military Road, Mumbai, Maharashtra 400 059,

Furosemide cas no:54-31-9

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