54-31-9|FurosemideProducts Supply - Chemical intermediates Network

Furosemide cas no:54-31-9

Synonyms: 5-(aminosulfonyl)-4-chloro-2-((2-furanylmethyl)amino)benzoic acid; 4-chloro-n-furfuryl-5-sulfamoylanthranilic acid; 2-furfurylamino-4-chloro-5-sulfamoylbenzoic acid

Identification

NameFurosemide
CAS54-31-9
Synonyms5-(aminosulfonyl)-4-chloro-2-((2-furanylmethyl)amino)benzoic acid; 4-chloro-n-furfuryl-5-sulfamoylanthranilic acid; 2-furfurylamino-4-chloro-5-sulfamoylbenzoic acid
EINECS(EC#)200-203-6
Molecular FormulaC12H11ClN2O5S
Molecular Weight330.74414

Chemical Properties

Appearancewhite powder
storage temp2-8°C

Safety Data

Hazard T:Toxic;
Risk R61
Safety

Hazard Codes of Furosemide (CAS NO.54-31-9): TF
Risk Statements: 61-39/23/24/25-11
61: May cause harm to the unborn child
39/23/24/25: Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed
11: Highly Flammable
Safety Statements: 7-16-45-53-36/37/39-22
7: Keep container tightly closed
16: Keep away from sources of ignition - No smoking
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
53: Avoid exposure - obtain special instruction before use
36/37/39: Wear suitable protective clothing, gloves and eye/face protection
22: Do not breathe dust
RIDADR: UN 1230 3/PG 2
WGK Germany: 3
RTECS: CB2625000

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	> 400mg/kg (400mg/kg)		Drugs in Japan Vol. 6, Pg. 725, 1982.
dog	LD50	oral	2gm/kg (2000mg/kg)		Drugs in Japan Vol. 6, Pg. 725, 1982.
human	TDLo	intravenous	1300ug/kg (1.3mg/kg)	CARDIAC: OTHER CHANGES VASCULAR: REGIONAL OR GENERAL ARTERIOLAR CONSTRICTION	Annals of Internal Medicine. Vol. 103, Pg. 1, 1985.
infant	TDLo	intravenous	1mg/kg/4H-I (1mg/kg)		Archives of Disease in Childhood. Vol. 59, Pg. 907, 1984.
man	TDLo	intravenous	29mg/kg (29mg/kg)	SENSE ORGANS AND SPECIAL SENSES: CHANGE IN ACUITY: EAR SENSE ORGANS AND SPECIAL SENSES: TINNITUS: EAR KIDNEY, URETER, AND BLADDER: URINE VOLUME DECREASED	New England Journal of Medicine. Vol. 282, Pg. 1413, 1970.
mouse	LD50	intravenous	308mg/kg (308mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 14, Pg. 44, 1964.
mouse	LD50	oral	2gm/kg (2000mg/kg)		European Patent Application. Vol. #0008367,
mouse	LD50	unreported	900mg/kg (900mg/kg)		European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 15, Pg. 386, 1980.
rabbit	LD50	intravenous	400mg/kg (400mg/kg)		Drugs in Japan Vol. 6, Pg. 725, 1982.
rabbit	LD50	oral	800mg/kg (800mg/kg)		Drugs in Japan Vol. 6, Pg. 725, 1982.
rat	LD50	intraperitoneal	800mg/kg (800mg/kg)		Acta Poloniae Pharmaceutica. For English translation, see APPFAR. Vol. 42, Pg. 199, 1985.
rat	LD50	intravenous	800mg/kg (800mg/kg)		Drugs in Japan Vol. 6, Pg. 725, 1982.
rat	LD50	oral	2600mg/kg (2600mg/kg)		Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971.
rat	LD50	subcutaneous	4600mg/kg (4600mg/kg)		Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 9, Pg. 759, 1967.
women	TDLo	intravenous	2500ug/kg/2M- (2.5mg/kg)	CARDIAC: PULSE RATE	Intensive Care Medicine. Vol. 12, Pg. 54, 1986.
women	TDLo	oral	6250ug/kg (6.25mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS	Journal of Toxicology, Clinical Toxicology. Vol. 31, Pg. 341, 1993.
women	TDLo	oral	120mg/kg/21W- (120mg/kg)	KIDNEY, URETER, AND BLADDER: INTERSTITIAL NEPHRITIS	Journal of the Royal Society of Medicine. Vol. 79, Pg. 239, 1986.

supplier list

Qingdao Chinaoil Co., Ltd: Tel:; Address: 22/F,Golden Light Tower,No.56, Xianggang Zhong Road, Qingdao 266071, China

K.-W.Pfannenschmidt GmbH: Tel:; Address:

KOA SHOJI CO., LTD.: Tel:+81-45-540-6985; Address: 17-5, Minowa-cho, 2-chome, Kohoku-ku, Yokohama-shi, Kanagawa, 223-0051, Japan

Leawell International Limited: Tel:+852-(2576)-0298; Address: 18/F Catic Plaza, 8 Causeway Road Causeway Bay,

Swiss Pharma Pvt. Ltd.: Tel:+91-(79)-26574432, 26577097; Address: 8B, Medicare Building, Ellisbridge, Ahmedabad, Gujarat 380 015,

Shanghai Coming Hi-Technology Co., Ltd.: Tel:+86-(21)-54821359; Address: 4th Floor, Building B. No.18, 1305 Huajing Road, Shanghai 200231,

Bravo Healthcare Ltd.: Tel:+91-(22)-27564051; Address: 208, Cosmos, Sector-11, Navi Mumbai, Maharashtra 400614,

Uma Brothers: Tel:+91-(22)-25004579; Address: C-110, Bhaveshwar Plaza, 189, L.B.S.Marg, Ghatkopar (W), Bombay, Maharashtra 400 086,

Sibram Pharmaceuticals: Tel:+91-(22)-67997876; Address: E-305, 3rd Floor Kailas Industrial Complex, Park Site, Vikhroli (West), Mumbai, Maharashtra 400079,

Parchem - Fine & Specialty Chemicals: Tel:+1-(914)-654-6800, 800-282-3982; Address: 415 Huguenot Street, New Rochelle, New York 10801,

Farmasino pharmaceuticals(Jiangsu)co.,ltd: Tel:+86-25-86907219; Address: 100 jianye road,nanjing(210004),china

NINGBO HI-TECH BIOCHEMICALS CO., LTD: Tel:86-574-27863817; Address: 13FA08 World Trade Center，DONGDU ROAD 29#, NIINGBO 315000 CHINA

Zhejiang Chemicals Import&Export Corporation: Tel:+86-571-28968550; Address: no.37 qingchun road hangzhou, china

Suzhou Yacoo Chemical Reagent Corporation: Tel:86-512-87666785; Address: A3 209 bio-bay No.218 Xinghu road suzhou industiral park

Jinlan Pharm-Drugs Technology Co., Limited: Tel:86-571-85829152; Address: Room 606, Fuyi Center, #298 Quanfuqiao Road, Jiang

Furosemide cas no:54-31-9

Directory

supplier list