1-Propanone,1,1'-(1,4-piperazinediyl)bis[3-bromo- cas no:54-91-1

Name1-Propanone,1,1'-(1,4-piperazinediyl)bis[3-bromo-
CAS54-91-1
SynonymsPiperazine,1,4-bis(3-bromo-1-oxopropyl)- (9CI); Piperazine, 1,4-bis(3-bromopropionyl)-(6CI,7CI,8CI); 1,4-Bis(3-bromopropionyl)piperazine; A 1803; Amedel;N,N'-Bis(3-bromopropionyl)piperazine; NSC-25154; Pipobroman; Vercyte
Molecular FormulaC10H16 Br2 N2 O2
Molecular Weight356.10

refractive index1.566

Safety

Poison by ingestion, subcutaneous and intraperitoneal routes. An experimental teratogen. Other experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of Br⁻ and NO_x. See also BROMIDES.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	285mg/kg (285mg/kg)		Acta Poloniae Pharmaceutica. For English translation, see APPFAR. Vol. 37, Pg. 249, 1980.
mouse	LD50	oral	382mg/kg (382mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 467, 1973.
mouse	LD50	subcutaneous	353mg/kg (353mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 467, 1973.
rat	LD50	intraperitoneal	140mg/kg (140mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 467, 1973.
rat	LD50	oral	220mg/kg (220mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 467, 1973.
rat	LD50	subcutaneous	139mg/kg (139mg/kg)		Drugs in Japan Vol. 6, Pg. 638, 1982.