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1,5-Pentamethylenetetrazole cas no:54-95-5

Synonyms: 6,7,8,9-Tetrahydro-5H-tetrazoloazepine; Pentylenetetrazole~6,7,8,9-Tetrahydro-5H-tetrazoloazepine; pentetrazol; leptazol; 1,5-Pentamethylene-1H-tetrazole; Pentylenetetrazole; Pentertrazol

Identification
Name1,5-Pentamethylenetetrazole
CAS54-95-5
Synonyms6,7,8,9-Tetrahydro-5H-tetrazoloazepine; Pentylenetetrazole~6,7,8,9-Tetrahydro-5H-tetrazoloazepine; pentetrazol; leptazol; 1,5-Pentamethylene-1H-tetrazole; Pentylenetetrazole; Pentertrazol
EINECS(EC#)200-219-3
Molecular FormulaC6H10N4
Molecular Weight138.17
Chemical Properties
Appearancewhite crystalline powder
refractive index1.494 (20 C)
storage temp−20°C
Sensitive Hygroscopic
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1
Safety Data

Hazard T:Toxic;
Risk R25;R36/37/38
Safety

A human poison by ingestion and intravenous routes. Poison experimentally by ingestion, intravenous, intraperitoneal, subcutaneous, rectal, and parenteral routes. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes: T
Risk Statements about 1,5-Pentamethylenetetrazole (CAS No.54-95-5):
R25 :Toxic if swallowed. 
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed. 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements about 1,5-Pentamethylenetetrazole (CAS No.54-95-5):
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
Attention:
1. Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture.
2. Handling: Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Do not allow contact with water. Keep from contact with moist air and steam.


Toxicity
1.    

orl-man LDLo:147 mg/kg

    85DCAI    Poisoning; Toxicology, Symptoms, Treatments. 2 (1970),73.
2.    

ivn-man LDLo:29 mg/kg

    85DCAI    Poisoning; Toxicology, Symptoms, Treatments. 2 (1970),73.
3.    

orl-rat LD50:140 mg/kg

    JPPMAB    Journal of Pharmacy and Pharmacology. 13 (1961),244.
4.    

ipr-rat LD50:62 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 18 (1971),185.
5.    

scu-rat LD50:85 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 18 (1971),185.
6.    

ivn-rat LD50:45 mg/kg

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 135 (1962),9.
7.    

rec-rat LD50:8 mg/kg AACRAT 46,395,67

8.    

orl-mus LD50:88 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 128 (1960),176.
9.    

ipr-mus LD50:71 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 128 (1960),176.
10.    

scu-mus LD50:80 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 8 (1958),190.
     

 

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