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Sodium thiocyanate cas no:540-72-7

Synonyms: Sodium Thiocyan;Sodium thiocyanide;Scyan;Natrium thiocyanat;Thiocyanate, sodium;Natriumrhodanid [German];Sodium thiocyanate solution (56% or less);Sodium rhodanate;Sodium sulfocyanate;Haimased;Thiocyanate sodium;Sodium thiocyanate solution;Sodium rhodanide;NaSCN;mono-dicalcium phosphate;

Identification
NameSodium thiocyanate
CAS540-72-7
SynonymsSodium Thiocyan;Sodium thiocyanide;Scyan;Natrium thiocyanat;Thiocyanate, sodium;Natriumrhodanid [German];Sodium thiocyanate solution (56% or less);Sodium rhodanate;Sodium sulfocyanate;Haimased;Thiocyanate sodium;Sodium thiocyanate solution;Sodium rhodanide;NaSCN;mono-dicalcium phosphate;
EINECS(EC#)208-754-4
Molecular FormulaNaSCN
Molecular Weight81.06
Chemical Properties
Appearancewhite crystalline powder
storage temp2-8°C
Sensitive Hygroscopic
Safety Data

Hazard Xn:Harmful;
Risk R20/21/22;R32;R52/53
Safety

Hazard Codes of Sodium thiocyanate (CAS NO.540-72-7): HarmfulXn
Risk Statements: 32-52/53-20/21/22 
R32: Contact with acid liberates very toxic gas. 
R52/53: Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. 
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 36/37-61-13 
S36/37: Wear suitable protective clothing and gloves. 
S61: Avoid release to the environment. Refer to special instructions / safety data sheets. 
S13: Keep away from food, drink and animal foodstuffs.
WGK Germany :1
RTECS: XL2275000
F: 3


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo intravenous 100mg/kg (100mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 169, Pg. 429, 1933.
guinea pig LDLo intraperitoneal 500mg/kg (500mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

BEHAVIORAL: EXCITEMENT
Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 169, Pg. 429, 1933.
guinea pig LDLo oral 600mg/kg (600mg/kg)   Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 29, Pg. 152, 1940.
guinea pig LDLo subcutaneous 500mg/kg (500mg/kg)   Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 29, Pg. 152, 1940.
mouse LD50 intraperitoneal 500mg/kg (500mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Japanese Journal of Pharmacology. Vol. 3, Pg. 99, 1954.
mouse LD50 intravenous 484mg/kg (484mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 29, Pg. 152, 1940.
mouse LD50 oral 362mg/kg (362mg/kg)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 106, 1982.
mouse LDLo subcutaneous 400mg/kg (400mg/kg)   Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 29, Pg. 152, 1940.
rabbit LDLo intravenous 100mg/kg (100mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 169, Pg. 429, 1933.
rabbit LDLo oral 750mg/kg (750mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 169, Pg. 429, 1933.
rabbit LDLo subcutaneous 200mg/kg (200mg/kg) AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: FOOD INTAKE (ANIMAL)
Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 152, Pg. 250, 1930.
rat LD50 intraperitoneal 540mg/kg (540mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Journal of Pharmacology and Experimental Therapeutics. Vol. 96, Pg. 416, 1949.
rat LD50 intratracheal 232mg/kg (232mg/kg)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 106, 1982.
rat LD50 oral 764mg/kg (764mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 29, Pg. 152, 1940.

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