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Ethyl thiocyanate;Thiocyanic acid ethyl ester cas no:542-90-5

Synonyms: Ethylthiocyanate; Thiocyanic acid ethyl ester;

Identification
NameEthyl thiocyanate;Thiocyanic acid ethyl ester
CAS542-90-5
SynonymsEthylthiocyanate; Thiocyanic acid ethyl ester;
EINECS(EC#)208-833-3
Molecular FormulaC3H5NS
Molecular Weight87.14
Chemical Properties
AppearanceVolatile liquid.
refractive index1.461-1.463
storage tempFlammables area
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass3.2
Safety Data

Hazard Xn:Harmful;
Risk R10;R20/21/22
Safety

Poison by ingestion, subcutaneous, intraperitoneal, and intravenous routes. When heated to decomposition it emits very toxic fumes of NOx and SOx. See also THIOCYANATES.

Hazard Codes: HarmfulXn
Risk Statements: 10-20/21/22-36/37/38
R10:Flammable. 
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed. 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36/37-24/25-16
S16:Keep away from sources of ignition. 
S36/37:Wear suitable protective clothing and gloves. 
S24/25:Avoid contact with skin and eyes. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
RIDADR UN: 2929 6.1/PG 2
WGK :Germany 3
RTECS :XK9900000
F :13-19-21
HazardClass :3.2
PackingGroup: III
HS Code :29309070


HS Code 29309070

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo oral 10mg/kg (10mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

GASTROINTESTINAL: OTHER CHANGES
Journal of Industrial Hygiene and Toxicology. Vol. 18, Pg. 310, 1936.
mouse LD50 intraperitoneal 10mg/kg (10mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Japanese Journal of Pharmacology. Vol. 3, Pg. 99, 1954.
mouse LD50 intravenous 18mg/kg (18mg/kg)   U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#02865,
mouse LD50 subcutaneous 70mg/kg (70mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Japanese Journal of Pharmacology. Vol. 3, Pg. 99, 1954.
rabbit LDLo subcutaneous 15mg/kg (15mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 150, Pg. 257, 1930.
rat LDLo oral 201mg/kg (201mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

LUNGS, THORAX, OR RESPIRATION: CYANOSIS
Journal of Industrial Hygiene and Toxicology. Vol. 18, Pg. 310, 1936.
rat LDLo skin 2512mg/kg (2512mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Journal of Industrial Hygiene and Toxicology. Vol. 18, Pg. 310, 1936.
rat LDLo subcutaneous 40mg/kg (40mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

LUNGS, THORAX, OR RESPIRATION: CYANOSIS
Journal of Industrial Hygiene and Toxicology. Vol. 18, Pg. 310, 1936.

 

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