548-00-5|Ethyl biscoumacetateProducts Supply - Chemical intermediates Network

Ethyl biscoumacetate cas no:548-00-5

Synonyms: Ethyl Biscoumacetate;DI(4-oxi-cymarinyl-3);Pelentan;Trombarin;Trombil;Trombolysan;2,2-bis(2-hydroxy-4-keto-chromen-3-yl)acetic acid ethyl ester;ethyl 2,2-bis(2-hydroxy-4-oxochromen-3-yl)acetate

Identification

NameEthyl biscoumacetate
CAS548-00-5
SynonymsEthyl Biscoumacetate;DI(4-oxi-cymarinyl-3);Pelentan;Trombarin;Trombil;Trombolysan;2,2-bis(2-hydroxy-4-keto-chromen-3-yl)acetic acid ethyl ester;ethyl 2,2-bis(2-hydroxy-4-oxochromen-3-yl)acetate
EINECS(EC#)208-940-5
Molecular FormulaC22H16O8
Molecular Weight408.36

Chemical Properties

refractive index1.688

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1(b)

Safety Data

Safety

Poison by intraperitoneal route. Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. Human reproductive effects by ingestion: developmental abnormalities of the cardiovascular system, stillbirth, and unspecified neonatal effects. An anticoagulant. See also WARFARIN and ESTERS. When heated to decomposition it emits acrid and irritating fumes.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	260mg/kg (260mg/kg)		Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 10, Pg. 303, 1951.
mouse	LD50	oral	750mg/kg (750mg/kg)		Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 222, Pg. 107, 1954.
mouse	LD50	subcutaneous	750mg/kg (750mg/kg)		Lancet. Vol. 2, Pg. 611, 1951.
rabbit	LD50	intraperitoneal	170mg/kg (170mg/kg)		Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 10, Pg. 303, 1951.
rabbit	LD50	oral	1gm/kg (1000mg/kg)		Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 222, Pg. 107, 1954.
rat	LD50	intraperitoneal	260mg/kg (260mg/kg)	BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) CARDIAC: CHANGE IN FORCE OF CONTRACTION LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 87, Pg. 402, 1951.
rat	LD50	oral	840mg/kg (840mg/kg)		Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 10, Pg. 303, 1951.

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Ethyl biscoumacetate cas no:548-00-5

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