1H-Benz[de]isoquinoline-1,3(2H)-dione,2-[2-(dimethylamino)ethyl]-5-nitro- cas no:54824-17-8

Synonyms: 3-Nitro-N-(2-dimethylaminoethyl)-1,8-naphthalimide;M 4212; M 4212 (pharmaceutical); Mitonafide; NSC 300288

Directory

Identification
Chemical Properties
Safety Data
Toxicity

Identification

Name1H-Benz[de]isoquinoline-1,3(2H)-dione,2-[2-(dimethylamino)ethyl]-5-nitro-
CAS54824-17-8
Synonyms3-Nitro-N-(2-dimethylaminoethyl)-1,8-naphthalimide;M 4212; M 4212 (pharmaceutical); Mitonafide; NSC 300288
Molecular FormulaC16H15 N3 O4
Molecular Weight349.80

Chemical Properties

refractive index1.667

Safety Data

Safety

Low toxicity by intraperitoneal route. Mutation data reported. When heated to decomposition Mitonafide (CAS NO.54824-17-8) emits toxic fumes of NO_x and HCl. See also AROMATIC AMINES.

Toxicity

1.	dnd-ham:ovr 10 µmol/L	JJIND8 JNCI, Journal of the National Cancer Institute. 70 (1983),1097.
2.	cyt-ham:ovr 1 µmol/L	JJIND8 JNCI, Journal of the National Cancer Institute. 70 (1983),1097.
3.	ipr-rat LD50:6500 µg/kg	CCPHDZ Cancer Chemotherapy and Pharmacology. 4 (1980),61.
4.	ipr-mus LD50:10,000 µg/kg	CCPHDZ Cancer Chemotherapy and Pharmacology. 4 (1980),61.

supplier list

Boc Sciences: Tel:1-631-5046093; Address: 45-16 Ramsey Road, Shirley, NY 11967, USA