Cinchonan-9-ol,6'-methoxy-, hydrobromide (1:1), (8a,9R)- cas no:549-49-5

NameCinchonan-9-ol,6'-methoxy-, hydrobromide (1:1), (8a,9R)-
CAS549-49-5
SynonymsCinchonan-9-ol,6'-methoxy-, monohydrobromide, (8a,9R)- (9CI); Quinine, monohydrobromide (8CI); Quinine hydrobromide
EINECS(EC#)208-967-2
Molecular FormulaC20H24 N2 O2 . Br H
Molecular Weight405.38

Hazardclass6.1(b)

Hazard Xn,Xi
Risk 20/21/22-36/37/38-42/43
Safety

Hazard Codes: Xn,Xi
Risk Statements: 20/21/22-36/37/38-42/43
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed. 
R36/37/38: Quinine hydrobromide (CAS NO.549-49-5) is irritating to eyes, respiratory system and skin. 
R42/43:May cause sensitization by inhalation and skin contact.
Safety Statements: 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing.
RIDADR: 1544
RTECS; VA7650000
HazardClass; 6.1(b)
PackingGroup: III

Poison by subcutaneous route. Moderately toxic by ingestion. When Quinine hydrobromide (CAS NO.549-49-5) is heated to decomposition, it emits toxic fumes of NO_x and HBr. See also QUININE.

HS Code 29392000

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
frog	LDLo	oral	30gm/kg (30000mg/kg)		"Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931.
frog	LDLo	subcutaneous	18gm/kg (18000mg/kg)		"Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931.
pigeon	LDLo	oral	6gm/kg (6000mg/kg)		"Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931.
pigeon	LDLo	subcutaneous	1gm/kg (1000mg/kg)		"Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931.
rabbit	LDLo	oral	750mg/kg (750mg/kg)		"Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931.
rabbit	LDLo	subcutaneous	250mg/kg (250mg/kg)		"Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931.