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Fluoxetine cas no:54910-89-3

Synonyms: Fluoxetine (TN);Fluoxetine (USAN);(+/-)-N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propylamine];Prozac;dl-3-(p-Trifluoromethylphenoxy)-N-methyl-3-phenylpropylamine;Pulvules;Fluval;3-(p-Trifluoromethylphenoxy)-N-methyl-3-phenylpropylamine;Benzenepropanamine, N-methyl-gamma-[4-(trifluoromethyl)phenoxy]-, (+/-)-;

Identification
NameFluoxetine
CAS54910-89-3
SynonymsFluoxetine (TN);Fluoxetine (USAN);(+/-)-N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propylamine];Prozac;dl-3-(p-Trifluoromethylphenoxy)-N-methyl-3-phenylpropylamine;Pulvules;Fluval;3-(p-Trifluoromethylphenoxy)-N-methyl-3-phenylpropylamine;Benzenepropanamine, N-methyl-gamma-[4-(trifluoromethyl)phenoxy]-, (+/-)-;
Molecular FormulaC17H18F3NO
Molecular Weight345.78707
Chemical Properties
storage tempKeep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
man TDLo oral 17mg/kg (17mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD American Journal of Emergency Medicine. Vol. 16, Pg. 328, 1998.
man TDLo oral 17mg/kg (17mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
American Journal of Emergency Medicine. Vol. 16, Pg. 328, 1998.
mouse LD50 intraperitoneal 87500ug/kg (87.5mg/kg) ? Drugs of the Future. Vol. 15, Pg. 1178, 1990.
mouse LD50 oral 464mg/kg (464mg/kg) ? Drugs of the Future. Vol. 15, Pg. 1178, 1990.
rat LD50 intraperitoneal 121mg/kg (121mg/kg) ? Drugs of the Future. Vol. 15, Pg. 1178, 1990.
rat LD50 oral 825mg/kg (825mg/kg) ? Drugs of the Future. Vol. 15, Pg. 1178, 1990.
women TDLo oral 2mg/kg/5D-I (2mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Archives of Internal Medicine. Vol. 156, Pg. 681, 1996.
women TDLo oral 16800ug/kg/6W (16.8mg/kg) BEHAVIORAL: MUSCLE WEAKNESS

BEHAVIORAL: ANTIPSYCHOTIC
Archives of Internal Medicine. Vol. 156, Pg. 681, 1996.
women TDLo oral 60mg/kg/21W-I (60mg/kg) ? American Journal of Psychiatry. Vol. 153, Pg. 134, 1996.
women TDLo oral 72mg/kg/26W-I (72mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Journal of Clinical Pyschopharmacology. Vol. 10, Pg. 343, 1990.

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