L-Epinephrine hydrochloride cas no:55-31-2
Synonyms: 1,2-Benzenediol,4-[(1R)-1-hydroxy-2-(methylamino)ethyl]-, hydrochloride (9CI);1,2-Benzenediol,4-[1-hydroxy-2-(methylamino)ethyl]-, hydrochloride, (R)-;Benzyl alcohol,3,4-dihydroxy-a-[(methylamino)methyl]-,hydrochloride, (-)- (8CI);(-)-Adrenaline hydrochloride;(-)-Epinephrinehydrochloride;Adrenalin chloride;Adrenalin hydrochloride;Adrenalinechlorhydrate;Adrenaline chloride;Adrenaline hydrochloride;Epinephrinechloride;Epinephrine hydrochloride;Gelatin-Epinephrine;Glaucon;SupranephrinSolution;Suprarenin hydrochloride;Tonogen;l-Adrenaline chloride;l-Adrenalinehydrochloride;l-Epinephrine chloride;l-Methylaminoethanolcatechol hydrochloride;
NameL-Epinephrine hydrochloride
CAS55-31-2
Synonyms1,2-Benzenediol,4-[(1R)-1-hydroxy-2-(methylamino)ethyl]-, hydrochloride (9CI);1,2-Benzenediol,4-[1-hydroxy-2-(methylamino)ethyl]-, hydrochloride, (R)-;Benzyl alcohol,3,4-dihydroxy-a-[(methylamino)methyl]-,hydrochloride, (-)- (8CI);(-)-Adrenaline hydrochloride;(-)-Epinephrinehydrochloride;Adrenalin chloride;Adrenalin hydrochloride;Adrenalinechlorhydrate;Adrenaline chloride;Adrenaline hydrochloride;Epinephrinechloride;Epinephrine hydrochloride;Gelatin-Epinephrine;Glaucon;SupranephrinSolution;Suprarenin hydrochloride;Tonogen;l-Adrenaline chloride;l-Adrenalinehydrochloride;l-Epinephrine chloride;l-Methylaminoethanolcatechol hydrochloride;
EINECS(EC#)200-230-3
Molecular FormulaC9H14ClNO3
Molecular Weight219.67
Appearancecrystals
storage tempKeep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(a)
Safety
Poison by ingestion, intravenous, subcutaneous, and intraperitoneal routes. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits very toxic fumes of Cl− and NOx. See also VASOTONIN and other adrenalin compounds.
Safety Information aboout L-Epinephrine hydrochloride (CAS NO.55-31-2):
RIDADR: 3249
HazardClass: 6.1(a)
PackingGroup: II
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| guinea pig |
LDLo |
intravenous |
200ug/kg (0.2mg/kg) |
|
Arzneimittel-Forschung. Drug Research. Vol. 13, Pg. 51, 1963. |
| guinea pig |
LDLo |
subcutaneous |
2mg/kg (2mg/kg) |
|
Arzneimittel-Forschung. Drug Research. Vol. 13, Pg. 51, 1963. |
| mouse |
LD50 |
intraperitoneal |
4664ug/kg (4.664mg/kg) |
VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION |
Journal of Pharmacology and Experimental Therapeutics. Vol. 90, Pg. 110, 1947. |
| mouse |
LD50 |
intravenous |
140ug/kg (0.14mg/kg) |
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
European Journal of Pharmacology. Vol. 9, Pg. 289, 1970. |
| mouse |
LD50 |
subcutaneous |
1980ug/kg (1.98mg/kg) |
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BEHAVIORAL: EXCITEMENT |
Journal of Pharmacology and Experimental Therapeutics. Vol. 87, Pg. 214, 1946. |
| mouse |
LDLo |
oral |
50mg/kg (50mg/kg) |
|
Arzneimittel-Forschung. Drug Research. Vol. 13, Pg. 51, 1963. |
| rat |
LD50 |
intraduodenal |
35mg/kg (35mg/kg) |
|
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 180, Pg. 155, 1969. |
| rat |
LD50 |
oral |
24mg/kg (24mg/kg) |
|
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 180, Pg. 155, 1969. |
| rat |
LD50 |
subcutaneous |
5mg/kg (5mg/kg) |
|
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 180, Pg. 155, 1969. |
| rat |
LDLo |
intravenous |
50ug/kg (0.05mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS |
Journal of Pharmacology and Experimental Therapeutics. Vol. 24, Pg. 101, 1925. |
