Pyridine,2-[(1E)-1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propen-1-yl]-, hydrochloride(1:1) cas no:550-70-9
Synonyms: Pyridine,2-[(1E)-1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]-, monohydrochloride(9CI); Pyridine, 2-[1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]-,monohydrochloride, (E)-; Pyridine, 2-[3-(1-pyrrolidinyl)-1-p-tolylpropenyl]-,monohydrochloride, (E)- (8CI); 295C51; Actidil; Actidilat; Actidilon; Entra; Pro-Actidil;Pro-Entra; Triprolidine hydrochloride; Venen;trans-1-(4-Methylphenyl)-1-(2-pyridyl)-3-pyrrolidinoprop-1-ene hydrochloride;trans-2-[3-(1-Pyrrolidinyl)-1-(p-tolyl)propenyl]pyridine hydrochloride
NamePyridine,2-[(1E)-1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propen-1-yl]-, hydrochloride(1:1)
CAS550-70-9
SynonymsPyridine,2-[(1E)-1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]-, monohydrochloride(9CI); Pyridine, 2-[1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]-,monohydrochloride, (E)-; Pyridine, 2-[3-(1-pyrrolidinyl)-1-p-tolylpropenyl]-,monohydrochloride, (E)- (8CI); 295C51; Actidil; Actidilat; Actidilon; Entra; Pro-Actidil;Pro-Entra; Triprolidine hydrochloride; Venen;trans-1-(4-Methylphenyl)-1-(2-pyridyl)-3-pyrrolidinoprop-1-ene hydrochloride;trans-2-[3-(1-Pyrrolidinyl)-1-(p-tolyl)propenyl]pyridine hydrochloride
EINECS(EC#)208-985-0
Molecular FormulaC19H22 N2 . Cl H
Molecular Weight314.89
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Hazard Xn
Risk 22-36/37/38
Safety
Poison by subcutaneous and intravenous routes. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx and HCl.
Safety Information of Triprolidine hydrochloride (CAS NO.550-70-9):
Hazard Codes: Xn.gif)
Risk Statements: 22-36/37/38
22: Harmful if swallowed
36: Irritating to the eyes
37: Irritating to the respiratory system
38: Irritating to the skin
Safety Statements: 26-36
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36: Wear suitable protective clothing
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| dog |
LD |
intravenous |
> 5mg/kg (5mg/kg) |
BEHAVIORAL: TREMOR
BEHAVIORAL: EXCITEMENT
LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
British Journal of Pharmacology and Chemotherapy. Vol. 8, Pg. 171, 1953. |
| mouse |
LD50 |
intravenous |
21mg/kg (21mg/kg) |
|
British Journal of Pharmacology and Chemotherapy. Vol. 8, Pg. 171, 1953. |
| mouse |
LD50 |
oral |
495mg/kg (495mg/kg) |
|
Drugs in Japan Vol. 6, Pg. 525, 1982. |
| mouse |
LD50 |
subcutaneous |
247mg/kg (247mg/kg) |
|
Drugs in Japan Vol. 6, Pg. 525, 1982. |
| rat |
LD50 |
oral |
840mg/kg (840mg/kg) |
|
Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 22, Pg. 375, 1980. |
