7,14-Methano-2H,11H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-11-one,dodecahydro-, (7S,7aR,14S,14aS)- cas no:550-90-3

Name7,14-Methano-2H,11H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-11-one,dodecahydro-, (7S,7aR,14S,14aS)-
CAS550-90-3
Synonyms7,14-Methano-2H,11H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-11-one,dodecahydro-, [7S-(7a,7aa,14a,14ab)]-; Lupanine (8CI); Lupanine, d- (6CI); (+)-2-Oxosparteine; (+)-Lupanine;2-Oxosparteine; 7,14-Methano-4H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-4-one,dodecahydro-, [7S-(7a,7ab,14a,14aa)]-; Lupanin; d-Lupanine
Molecular FormulaC15H24 N2 O
Molecular Weight248.36

refractive index1.581

Safety

Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NO_x.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LDLo	intraperitoneal	22mg/kg (22mg/kg)		Journal of Agricultural Research Vol. 32, Pg. 51, 1926.
guinea pig	LDLo	intravenous	78mg/kg (78mg/kg)	BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)	Planta Medica. Vol. 50, Pg. 420, 1984.
mouse	LD50	intraperitoneal	175mg/kg (175mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Planta Medica. Vol. 50, Pg. 420, 1984.
mouse	LD50	oral	410mg/kg (410mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Planta Medica. Vol. 50, Pg. 420, 1984.
rat	LD50	intraperitoneal	177mg/kg (177mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS	JAT, Journal of Applied Toxicology. Vol. 7, Pg. 51, 1987.
rat	LD50	oral	1440mg/kg (1440mg/kg)		Archives Internationales de Pharmacodynamie et de Therapie. Vol. 210, Pg. 27, 1974.