1,2,3-Propanetricarboxylicacid, 2-hydroxy-, potassium sodium salt, hydrate (5:6:6:?) cas no:55049-48-4

Name1,2,3-Propanetricarboxylicacid, 2-hydroxy-, potassium sodium salt, hydrate (5:6:6:?)
CAS55049-48-4
Synonyms1,2,3-Propanetricarboxylicacid, 2-hydroxy-, potassium sodium salt (5:6:6), hydrate (9CI); CG 120;Solimok; Uralyt U
Molecular FormulaC6H8 O7 . x H2 O . 6/5 K . 6/5 Na
Molecular Weight582.4789

Safety

Poison by intravenous route. Moderately toxic by subcutaneous route. Sodium citrate, potassium citrate, citric acid (2:2:1) (CAS NO.55049-48-4) is mildly toxic by ingestion. When heated to decomposition it emits toxic fumes of K₂O and Na₂O.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	245mg/kg (245mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Kiso to Rinsho. Clinical Report. Vol. 20, Pg. 4455, 1986.
dog	LD50	oral	> 5gm/kg (5000mg/kg)	BEHAVIORAL: ATAXIA GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Kiso to Rinsho. Clinical Report. Vol. 20, Pg. 4455, 1986.
mouse	LD50	intraperitoneal	1297mg/kg (1297mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Kiso to Rinsho. Clinical Report. Vol. 20, Pg. 4455, 1986.
mouse	LD50	intravenous	194mg/kg (194mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Kiso to Rinsho. Clinical Report. Vol. 20, Pg. 4455, 1986.
mouse	LD50	oral	8954mg/kg (8954mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Kiso to Rinsho. Clinical Report. Vol. 20, Pg. 4455, 1986.
mouse	LD50	subcutaneous	1965mg/kg (1965mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Kiso to Rinsho. Clinical Report. Vol. 20, Pg. 4455, 1986.
rabbit	LD50	intravenous	181mg/kg (181mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Kiso to Rinsho. Clinical Report. Vol. 20, Pg. 4455, 1986.
rabbit	LD50	oral	4090mg/kg (4090mg/kg)	BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: ATAXIA	Kiso to Rinsho. Clinical Report. Vol. 20, Pg. 4455, 1986.
rat	LD50	intraperitoneal	1310mg/kg (1310mg/kg)		Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 24, Pg. 1665, 1982.
rat	LD50	intravenous	143mg/kg (143mg/kg)		Oyo Yakuri. Pharmacometrics. Vol. 21, Pg. 715, 1981.
rat	LD50	oral	7200mg/kg (7200mg/kg)		Oyo Yakuri. Pharmacometrics. Vol. 21, Pg. 715, 1981.
rat	LD50	subcutaneous	1848mg/kg (1848mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Kiso to Rinsho. Clinical Report. Vol. 20, Pg. 4455, 1986.