RFCNU cas no:55102-44-8
Synonyms: Urea,N-(2-chloroethyl)-N'-[2,3-O-(1-methylethylidene)- 5-O-(4-nitrobenzoyl)-Dribofuranosyl]- N-nitroso-;Urea, N-(2-chloroethyl)-N-[2, 3-O-(1-methylethylidene)-5-O-(4-nitrobenzoyl)-D-ribofuranosyl]-N-n itroso-;Bofumustine;Furo[3,4-d]-1,3-dioxole, urea deriv.;[2-[(2-chloroethyl-nitroso-carbamoyl)amino]-7,7-dimethyl-3,6,8-trioxabicyclo[3.3.0]oct-4-yl]methyl 4-nitrobenzoate;ICIG 1105;(CHLORO-2-ETIL)-1-(RIBOFURANOSILISOPROPILIDENE-2′,3′-PARANITROBENZOATO)-3-NITROSOUREA;(CHLORO-2-ETHYL)-1-(RIBOFURANOSYLISOPROPY-LIDENE-2′-3′-PARANITROBENZOATE-5′)-3-NITROSOUREA;I.C.I.G. 1105;
NameRFCNU
CAS55102-44-8
SynonymsUrea,N-(2-chloroethyl)-N'-[2,3-O-(1-methylethylidene)- 5-O-(4-nitrobenzoyl)-Dribofuranosyl]- N-nitroso-;Urea, N-(2-chloroethyl)-N-[2, 3-O-(1-methylethylidene)-5-O-(4-nitrobenzoyl)-D-ribofuranosyl]-N-n itroso-;Bofumustine;Furo[3,4-d]-1,3-dioxole, urea deriv.;[2-[(2-chloroethyl-nitroso-carbamoyl)amino]-7,7-dimethyl-3,6,8-trioxabicyclo[3.3.0]oct-4-yl]methyl 4-nitrobenzoate;ICIG 1105;(CHLORO-2-ETIL)-1-(RIBOFURANOSILISOPROPILIDENE-2′,3′-PARANITROBENZOATO)-3-NITROSOUREA;(CHLORO-2-ETHYL)-1-(RIBOFURANOSYLISOPROPY-LIDENE-2′-3′-PARANITROBENZOATE-5′)-3-NITROSOUREA;I.C.I.G. 1105;
Molecular FormulaC18H21ClN4O9
Molecular Weight472.88
refractive index1.647
Safety
Poison by intraperitoneal route. Human mutation data reported. Many N-nitroso compounds are carcinogens. When RFCNU (CAS NO.55102-44-8) is heated to decomposition ,it emits toxic fumes of Cl− and NOx. See also N-NITROSO COMPOUNDS.
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intraperitoneal |
90mg/kg (90mg/kg) |
|
INSERM Symposium. Vol. 19, Pg. 123, 1981. |
