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Praziquantel cas no:55268-74-1

Synonyms: Drontal;Prestwick_402;4H-Pyrazino(2,1-a)isoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-;Biltricide (TN);2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino(2,1-a)isoquinolin-4-one;5-24-03-00361 (Beilstein Handbook Reference);2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro- 4H-pyrazino[2,1-a]-isoquinolin-4-one;Drontal Plus;Droncit;Praziquantel (JAN/USP);Cutter;

Identification
NamePraziquantel
CAS55268-74-1
SynonymsDrontal;Prestwick_402;4H-Pyrazino(2,1-a)isoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-;Biltricide (TN);2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino(2,1-a)isoquinolin-4-one;5-24-03-00361 (Beilstein Handbook Reference);2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro- 4H-pyrazino[2,1-a]-isoquinolin-4-one;Drontal Plus;Droncit;Praziquantel (JAN/USP);Cutter;
EINECS(EC#)259-559-6
Molecular FormulaC19H24N2O2
Molecular Weight312.40606
Chemical Properties
AppearanceWHITE OR PRACTICALLY WHITE CRYSTALLINE POWDER
storage temp?20°C
Safety Data

Hazard F: Flammable;C: Corrosive;
Risk R11
Safety

Hazard Codes of Biltricide (CAS NO.55268-74-1):?FlammableF,CorrosiveC
Risk Statements: 11-34?
R11: Highly flammable.?
R34: Causes burns.
Safety Statements: 16-26-36/37/39-45?
S16: Keep away from sources of ignition.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.?
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
WGK Germany: 1
RTECS: UQ4150000
Poison by intraperitoneal route. Moderately toxic by ingestion and other routes. Human mutation data reported. When Biltricide was heated to decomposition, it emits toxic fumes of NOx.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 oral > 200mg/kg (200mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 555, 1981.
mouse LD50 intramuscular > 2gm/kg (2000mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 555, 1981.
mouse LD50 intraperitoneal 376mg/kg (376mg/kg) ? Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 20, Pg. 228, 1989.
mouse LD50 oral 2454mg/kg (2454mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 555, 1981.
mouse LD50 subcutaneous 7172mg/kg (7172mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 555, 1981.
rabbit LD50 oral 1050mg/kg (1050mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 555, 1981.
rat LD50 intramuscular > 2gm/kg (2000mg/kg) ? Drugs in Japan Vol. -, Pg. 965, 1990.
rat LD50 intraperitoneal 586mg/kg (586mg/kg) ? Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 20, Pg. 228, 1989.
rat LD50 oral 2840mg/kg (2840mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 555, 1981.
rat LD50 subcutaneous > 16gm/kg (16000mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 555, 1981.

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