Praziquantel cas no:55268-74-1
Synonyms: Drontal;Prestwick_402;4H-Pyrazino(2,1-a)isoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-;Biltricide (TN);2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino(2,1-a)isoquinolin-4-one;5-24-03-00361 (Beilstein Handbook Reference);2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro- 4H-pyrazino[2,1-a]-isoquinolin-4-one;Drontal Plus;Droncit;Praziquantel (JAN/USP);Cutter;
NamePraziquantel
CAS55268-74-1
SynonymsDrontal;Prestwick_402;4H-Pyrazino(2,1-a)isoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-;Biltricide (TN);2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino(2,1-a)isoquinolin-4-one;5-24-03-00361 (Beilstein Handbook Reference);2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro- 4H-pyrazino[2,1-a]-isoquinolin-4-one;Drontal Plus;Droncit;Praziquantel (JAN/USP);Cutter;
EINECS(EC#)259-559-6
Molecular FormulaC19H24N2O2
Molecular Weight312.40606
AppearanceWHITE OR PRACTICALLY WHITE CRYSTALLINE POWDER
storage temp?20°C
Hazard F: Flammable;C: Corrosive;
Risk R11
Safety
Hazard Codes of Biltricide (CAS NO.55268-74-1):?
F,
C
Risk Statements: 11-34?
R11: Highly flammable.?
R34: Causes burns.
Safety Statements: 16-26-36/37/39-45?
S16: Keep away from sources of ignition.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.?
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
WGK Germany: 1
RTECS: UQ4150000
Poison by intraperitoneal route. Moderately toxic by ingestion and other routes. Human mutation data reported. When Biltricide was heated to decomposition, it emits toxic fumes of NOx.
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| dog |
LD50 |
oral |
> 200mg/kg (200mg/kg) |
? |
Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 555, 1981. |
| mouse |
LD50 |
intramuscular |
> 2gm/kg (2000mg/kg) |
? |
Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 555, 1981. |
| mouse |
LD50 |
intraperitoneal |
376mg/kg (376mg/kg) |
? |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 20, Pg. 228, 1989. |
| mouse |
LD50 |
oral |
2454mg/kg (2454mg/kg) |
? |
Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 555, 1981. |
| mouse |
LD50 |
subcutaneous |
7172mg/kg (7172mg/kg) |
? |
Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 555, 1981. |
| rabbit |
LD50 |
oral |
1050mg/kg (1050mg/kg) |
? |
Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 555, 1981. |
| rat |
LD50 |
intramuscular |
> 2gm/kg (2000mg/kg) |
? |
Drugs in Japan Vol. -, Pg. 965, 1990. |
| rat |
LD50 |
intraperitoneal |
586mg/kg (586mg/kg) |
? |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 20, Pg. 228, 1989. |
| rat |
LD50 |
oral |
2840mg/kg (2840mg/kg) |
? |
Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 555, 1981. |
| rat |
LD50 |
subcutaneous |
> 16gm/kg (16000mg/kg) |
? |
Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 555, 1981. |
