55268-74-1|PraziquantelProducts Supply - Chemical intermediates Network

Praziquantel cas no:55268-74-1

Synonyms: Drontal;Prestwick_402;4H-Pyrazino(2,1-a)isoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-;Biltricide (TN);2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino(2,1-a)isoquinolin-4-one;5-24-03-00361 (Beilstein Handbook Reference);2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro- 4H-pyrazino[2,1-a]-isoquinolin-4-one;Drontal Plus;Droncit;Praziquantel (JAN/USP);Cutter;

Identification

NamePraziquantel
CAS55268-74-1
SynonymsDrontal;Prestwick_402;4H-Pyrazino(2,1-a)isoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-;Biltricide (TN);2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino(2,1-a)isoquinolin-4-one;5-24-03-00361 (Beilstein Handbook Reference);2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro- 4H-pyrazino[2,1-a]-isoquinolin-4-one;Drontal Plus;Droncit;Praziquantel (JAN/USP);Cutter;
EINECS(EC#)259-559-6
Molecular FormulaC₁₉H₂₄N₂O₂
Molecular Weight312.40606

Chemical Properties

AppearanceWHITE OR PRACTICALLY WHITE CRYSTALLINE POWDER
storage temp?20°C

Safety Data

Hazard F: Flammable;C: Corrosive;
Risk R11
Safety

Hazard Codes of Biltricide (CAS NO.55268-74-1):?F, Corrosive C
Risk Statements: 11-34?
R11: Highly flammable.?
R34: Causes burns.
Safety Statements: 16-26-36/37/39-45?
S16: Keep away from sources of ignition.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.?
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
WGK Germany: 1
RTECS: UQ4150000
Poison by intraperitoneal route. Moderately toxic by ingestion and other routes. Human mutation data reported. When Biltricide was heated to decomposition, it emits toxic fumes of NO_x.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	oral	> 200mg/kg (200mg/kg)	?	Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 555, 1981.
mouse	LD50	intramuscular	> 2gm/kg (2000mg/kg)	?	Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 555, 1981.
mouse	LD50	intraperitoneal	376mg/kg (376mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 20, Pg. 228, 1989.
mouse	LD50	oral	2454mg/kg (2454mg/kg)	?	Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 555, 1981.
mouse	LD50	subcutaneous	7172mg/kg (7172mg/kg)	?	Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 555, 1981.
rabbit	LD50	oral	1050mg/kg (1050mg/kg)	?	Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 555, 1981.
rat	LD50	intramuscular	> 2gm/kg (2000mg/kg)	?	Drugs in Japan Vol. -, Pg. 965, 1990.
rat	LD50	intraperitoneal	586mg/kg (586mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 20, Pg. 228, 1989.
rat	LD50	oral	2840mg/kg (2840mg/kg)	?	Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 555, 1981.
rat	LD50	subcutaneous	> 16gm/kg (16000mg/kg)	?	Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 555, 1981.

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Praziquantel cas no:55268-74-1

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