55268-75-2|5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,3-[[(aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-furanyl)-2-(methoxyimino)acetyl]amino]-8-oxo-,(6R,7R)-Products Supply

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,3-[[(aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-furanyl)-2-(methoxyimino)acetyl]amino]-8-oxo-,(6R,7R)- cas no:55268-75-2

Synonyms: Cefaloxime;Cefasyn;Cefuroxim;Cefuroxime acid;Ketocef;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,3-[[(aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-furanyl(methoxyimino)acetyl]amino]-8-oxo-,(6R,7R)- (9CI);5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,3-[[(aminocarbonyl)oxy]methyl]-7-[[2-furanyl(methoxyimino)acetyl]amino]-8-oxo-,[6R-[6a,7b(Z)]]-;Biofuroksym;Biofuroxim;

Identification

Name5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,3-[[(aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-furanyl)-2-(methoxyimino)acetyl]amino]-8-oxo-,(6R,7R)-
CAS55268-75-2
SynonymsCefaloxime;Cefasyn;Cefuroxim;Cefuroxime acid;Ketocef;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,3-[[(aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-furanyl(methoxyimino)acetyl]amino]-8-oxo-,(6R,7R)- (9CI);5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,3-[[(aminocarbonyl)oxy]methyl]-7-[[2-furanyl(methoxyimino)acetyl]amino]-8-oxo-,[6R-[6a,7b(Z)]]-;Biofuroksym;Biofuroxim;
EINECS(EC#)259-560-1
Molecular FormulaC₁₆H₁₆N₄O₈S
Molecular Weight424.39

Chemical Properties

AppearanceWhite to ivory white crystalline powder
refractive index1.665

Safety Data

Hazard Xn
Risk R42/43
Safety

Mildly toxic by intravenous route. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of SO_x and NO_x.
Safety Information of Cefuroxime (CAS NO.55268-75-2):
Hazard Codes: Xn
Risk Statements: 42/43
42: May cause sensitization by inhalation
43: May cause sensitization by skin contact
Safety Statements: 22-24-37-45
22: Do not breathe dust
24: Avoid contact with skin
37: Wear suitable gloves
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
man	TDLo	intravenous	64mg/kg/16H-I (64mg/kg)	BEHAVIORAL: TOXIC PSYCHOSIS	Lancet. Vol. 1, Pg. 965, 1984.
mouse	LD50	intramuscular	> 2gm/kg (2000mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: ATAXIA	Chemotherapy Vol. 27(Suppl,
mouse	LD50	intraperitoneal	> 10gm/kg (10000mg/kg)	GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Chemotherapy Vol. 27(Suppl,
mouse	LD50	intravenous	10400mg/kg (10400mg/kg)		Drugs. International Journal of Current Therapeutics and Applied Pharmacology Reviews. Vol. 17, Pg. 233, 1979.
mouse	LD50	oral	> 10gm/kg (10000mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: ATAXIA	Chemotherapy Vol. 27(Suppl,
mouse	LD50	subcutaneous	> 10gm/kg (10000mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: ATAXIA	Chemotherapy Vol. 27(Suppl,
rabbit	LD50	intramuscular	> 300mg/kg (300mg/kg)		Chemotherapy Vol. 27(Suppl,
rabbit	LD50	intravenous	> 1500mg/kg (1500mg/kg)	BEHAVIORAL: FOOD INTAKE (ANIMAL) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Chemotherapy Vol. 27(Suppl,
rat	LD50	intramuscular	> 2gm/kg (2000mg/kg)		Chemotherapy Vol. 27(Suppl,
rat	LD50	intraperitoneal	> 10gm/kg (10000mg/kg)		Chemotherapy Vol. 27(Suppl,
rat	LD50	intravenous	> 8gm/kg (8000mg/kg)		Chemotherapy Vol. 27(Suppl,
rat	LD50	oral	10gm/kg (10000mg/kg)		Chemotherapy Vol. 27(Suppl,
rat	LD50	subcutaneous	> 10gm/kg (10000mg/kg)		Chemotherapy Vol. 27(Suppl,

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N-Techem International Co.Ltd.: Tel:; Address: Room 803, B Building, LiYuanShangDu, 39#, 158 Lane, HuanCheng XiLu, Ningbo, Zhejiang, China

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Inter-Chemical Ltd.: Tel:+86-(755)-82187211, 82192202; Address: B-1108/1109, Tian An International Bldg., RenMin Nan Road, ShenZhen 518005,

Chemner Pharma: Tel:+86-(23)-62482345; Address: 668# International Exhibtion and Conference Center, Chongqing, Sichuan 400060,

Vipro Lifescience Pvt. Ltd.: Tel:+91-(79)-26870952, 26870954; Address: 402-403, Sarthik-2, Opp. Rajpath Club, S.G. Road, Ahmedabad, Gujarat 380054,

M. S. Pharmachem: Tel:+91-(22)-32910305; Address: D-1/4, 604, Yamuna Nagar, Oshiwara, Andheri [West], Mumbai, Maharashtra,

Trust & We Co., Ltd.: Tel:86-21-61551611; Address: 601, No. 1, 2277 Nong, Zu Chongzhi Road, Zhangjiang Hightech. Park, Pudong, Shanghai, China.

Shanghai Xunxin Chemical Co., Ltd: Tel:+86-(21)-38218795; Address: 580 Lane, Kanghong Road, Pudong New District, Shanghai 201315,

Hebei Baiqi Pharmaceutical and Chemical Co., Ltd.: Tel:+86-(311)-8528-3311; Address: Rm A-11D, Zhuye Building, Changjiang Road, Shijiazhaung,

Facus Pharmaceutical Co., Ltd.: Tel:+86-(574)-6237-8411; Address: 24Fl, Yuanjing Building, Beilun, Ningbo, Zhejiang 315800,

Yongning Pharma: Tel:+86-(576)-8408-2118, 8423-7796, 8408-2281; Address: No.4, Meihuajing Rd., Huangyan, Taizhou, Zhejiang 318020,

Watson International Ltd.: Tel:+86-(512)-55117610; Address: Room 1209, Asia Pacific Plaza, Huaqiao International Business Park, Kunshan, Jiangsu 215332,

Taizhou Xingcheng Chempharm Co., Ltd.: Tel:+86-(576)-88886292, 88525005; Address: B Area. 10 Floor.Yaodadasha. 289#.Shifu Road, Taizhou, Zhejiang 318000,

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,3-[[(aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-furanyl)-2-(methoxyimino)acetyl]amino]-8-oxo-,(6R,7R)- cas no:55268-75-2

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