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Benzenamine,N,N-bis(2-chloroethyl)- cas no:553-27-5

Synonyms: Aniline,N,N-bis(2-chloroethyl)- (6CI,7CI,8CI); Aniline mustard; Lymphochin; Lymphocin;Lymphoquin; N,N-Bis(2-chloroethyl)aniline; N,N-Bis(2'-chloroethyl)aniline;N,N-Di(2-chloroethyl)aniline; NCS-18429; NSC 18429; b,b'-Dichlorodiethylaniline

Identification
NameBenzenamine,N,N-bis(2-chloroethyl)-
CAS553-27-5
SynonymsAniline,N,N-bis(2-chloroethyl)- (6CI,7CI,8CI); Aniline mustard; Lymphochin; Lymphocin;Lymphoquin; N,N-Bis(2-chloroethyl)aniline; N,N-Bis(2'-chloroethyl)aniline;N,N-Di(2-chloroethyl)aniline; NCS-18429; NSC 18429; b,b'-Dichlorodiethylaniline
Molecular FormulaC10H13 Cl2 N
Molecular Weight 218.14
Chemical Properties
refractive index1.563
Safety Data

Safety

Poison by inhalation, ingestion, and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits toxic fumes of Cl and NOx. See also ANILINE DYES.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mammal (species unspecified) LD50 unreported 100mg/kg (100mg/kg)   Pharmaceutical Bulletin. Vol. 5, Pg. 203, 1957.
mouse LCLo inhalation 500mg/m3/10M (500mg/m3) BEHAVIORAL: IRRITABILITY

LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA
National Defense Research Committee, Office of Scientific Research and Development, Progress Report.Vol. NDCrc-132, Pg. DEC1942,
mouse LD50 intraperitoneal 52mg/kg (52mg/kg)   Progress Report Submitted to the National Cancer Institute by Mason Research Institute. Vol. -, Pg. 469, 1969.
mouse LD50 oral 123mg/kg (123mg/kg)   Progress Report Submitted to the National Cancer Institute by Mason Research Institute. Vol. -, Pg. 469, 1969.
mouse LD50 parenteral 125mg/kg (125mg/kg)   Pharmazie in Unserer Zeit. Vol. 5, Pg. 41, 1976.
rat LD50 intraperitoneal 80mg/kg (80mg/kg)   Journal of Medicinal Chemistry. Vol. 8, Pg. 167, 1965.
rat LD50 oral 239mg/kg (239mg/kg)   Progress Report Submitted to the National Cancer Institute by Mason Research Institute. Vol. -, Pg. 469, 1969.

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