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Safety
Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. When Phenylramidol (CAS NO.553-69-5) is heated to decomposition ,it emits toxic fumes of NOx.
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 355mg/kg (355mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ANTIPSYCHOTIC LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES |
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 141, Pg. 83, 1963. |
| mouse | LD50 | intravenous | 124mg/kg (124mg/kg) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 141, Pg. 83, 1963. |
| mouse | LD50 | oral | 1850mg/kg (1850mg/kg) | Bollettino Chimico Farmaceutico. Vol. 103, Pg. 245, 1964. | |
| mouse | LD50 | subcutaneous | 405mg/kg (405mg/kg) | BEHAVIORAL: ANTICONVULSANT | Acta Pharmacologica et Toxicologica. Vol. 19, Pg. 247, 1962. |
| rat | LD50 | oral | 756mg/kg (756mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ANTIPSYCHOTIC LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES |
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 130, Pg. 280, 1961. |
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