| man |
TDLo |
oral |
1071mg/kg/22W (1071mg/kg) |
SKIN AND APPENDAGES (SKIN): "DERMATITIS, ALLERGIC: AFTER SYSTEMIC EXPOSURE" |
CUTIS; Cutaneous Medicine for the Practitioner. Vol. 38, Pg. 187, 1986. |
| mouse |
LD50 |
intraperitoneal |
150mg/kg (150mg/kg) |
CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP
VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION |
Journal of Medicinal Chemistry. Vol. 20, Pg. 1378, 1977. |
| mouse |
LD50 |
intravenous |
1700mg/kg (1700mg/kg) |
? |
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 56, Pg. 1103, 1960. |
| mouse |
LD50 |
oral |
5300mg/kg (5300mg/kg) |
? |
Drugs in Japan Vol. -, Pg. 1178, 1990. |
| rabbit |
LD50 |
intravenous |
713mg/kg (713mg/kg) |
? |
"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 348, 1972. |
| rabbit |
LD50 |
oral |
713mg/kg (713mg/kg) |
? |
"Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973Vol. -, Pg. 162, 1973. |
| rat |
LD50 |
intraperitoneal |
300mg/kg (300mg/kg) |
? |
"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 348, 1972. |
| rat |
LD50 |
oral |
5gm/kg (5000mg/kg) |
? |
"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 348, 1972. |
| women |
TDLo |
oral |
900mg/kg/13W- (900mg/kg) |
BEHAVIORAL: TREMOR |
Neurology. Vol. 35, Pg. 1668, 1985. |
| women |
TDLo |
oral |
1830mg/kg/17W (1830mg/kg) |
PERIPHERAL NERVE AND SENSATION: FASCICULATIONS
BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"
BEHAVIORAL: TREMOR |
South African Medical Journal. Vol. 65, Pg. 194, 1984. |
| women |
TDLo |
oral |
44gm/kg/3Y-I (44000mg/kg) |
GASTROINTESTINAL: NECROTIC GHANGES |
American Heart Journal. Vol. 105, Pg. 1037, 1983. |
