555-30-6|L-Tyrosine, 3-hydroxy-a-methyl-Products Supply

L-Tyrosine, 3-hydroxy-a-methyl- cas no:555-30-6

Synonyms: Alanine,3-(3,4-dihydroxyphenyl)-2-methyl-, L- (8CI);(-)-Methyldopa;(S)-(-)-a-Methyldopa;2-Methyl-3-(3,4-dihydroxyphenyl)alanine;Aldometil;Alphamethyldopa;Baypresol;Dopatec;Equibar;L-(-)-a-Methyl-b-(3,4-dihydroxyphenyl)alanine;L-3,4-Dihydroxy-a-methylphenylalanine;Levo-3-(3,4-Dihydroxyphenyl)-2-methylalanine;Medomet;Medopa;Methoplain;Methyldopa;NSC 169916;Presinol;Presolisin;

Identification

NameL-Tyrosine, 3-hydroxy-a-methyl-
CAS555-30-6
SynonymsAlanine,3-(3,4-dihydroxyphenyl)-2-methyl-, L- (8CI);(-)-Methyldopa;(S)-(-)-a-Methyldopa;2-Methyl-3-(3,4-dihydroxyphenyl)alanine;Aldometil;Alphamethyldopa;Baypresol;Dopatec;Equibar;L-(-)-a-Methyl-b-(3,4-dihydroxyphenyl)alanine;L-3,4-Dihydroxy-a-methylphenylalanine;Levo-3-(3,4-Dihydroxyphenyl)-2-methylalanine;Medomet;Medopa;Methoplain;Methyldopa;NSC 169916;Presinol;Presolisin;
EINECS(EC#)209-089-2
Molecular FormulaC₁₀H₁₃NO₄
Molecular Weight211.22

Chemical Properties

AppearanceColorless or almost colorless crystals or white to yellowish-white fine powder. Almost tasteless. In the sesquihydrate form.
refractive index-14 ° (C=1, H2O)
storage tempKeep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.

Safety Data

Safety

WGK: Germany 3
RTECS :YP2860000
F :10-23

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
man	TDLo	oral	1071mg/kg/22W (1071mg/kg)	SKIN AND APPENDAGES (SKIN): "DERMATITIS, ALLERGIC: AFTER SYSTEMIC EXPOSURE"	CUTIS; Cutaneous Medicine for the Practitioner. Vol. 38, Pg. 187, 1986.
mouse	LD50	intraperitoneal	150mg/kg (150mg/kg)	CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION	Journal of Medicinal Chemistry. Vol. 20, Pg. 1378, 1977.
mouse	LD50	intravenous	1700mg/kg (1700mg/kg)	?	Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 56, Pg. 1103, 1960.
mouse	LD50	oral	5300mg/kg (5300mg/kg)	?	Drugs in Japan Vol. -, Pg. 1178, 1990.
rabbit	LD50	intravenous	713mg/kg (713mg/kg)	?	"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 348, 1972.
rabbit	LD50	oral	713mg/kg (713mg/kg)	?	"Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973Vol. -, Pg. 162, 1973.
rat	LD50	intraperitoneal	300mg/kg (300mg/kg)	?	"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 348, 1972.
rat	LD50	oral	5gm/kg (5000mg/kg)	?	"Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 348, 1972.
women	TDLo	oral	900mg/kg/13W- (900mg/kg)	BEHAVIORAL: TREMOR	Neurology. Vol. 35, Pg. 1668, 1985.
women	TDLo	oral	1830mg/kg/17W (1830mg/kg)	PERIPHERAL NERVE AND SENSATION: FASCICULATIONS BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" BEHAVIORAL: TREMOR	South African Medical Journal. Vol. 65, Pg. 194, 1984.
women	TDLo	oral	44gm/kg/3Y-I (44000mg/kg)	GASTROINTESTINAL: NECROTIC GHANGES	American Heart Journal. Vol. 105, Pg. 1037, 1983.

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L-Tyrosine, 3-hydroxy-a-methyl- cas no:555-30-6

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