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N-Methyl-N-propargylbenzylamine cas no:555-57-7

Synonyms: Pargyline; benzyl(methyl)prop-2-ynylamine

Identification
NameN-Methyl-N-propargylbenzylamine
CAS555-57-7
SynonymsPargyline; benzyl(methyl)prop-2-ynylamine
EINECS(EC#)209-101-6 (Base) 206-175
Molecular FormulaC11H13N
Molecular Weight159.23
Chemical Properties
Appearancewhite to off-white crystalline powder
refractive indexn20/D 1.522(lit.)
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard Xn:Harmful;
Risk R22
Safety

Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. Human systemic effects by ingestion: eye lachrymation, olfactory and pulmonary effects. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx. See also AMINES.
Hazard Codes:
ToxicT
Risk Statements:
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed. 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements:
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2810 6.1/PG 3
WGK Germany: 3
RTECS: DP6475000
HazardClass: 6.1(b)
PackingGroup: III


Toxicity
1.    

orl-chd TDLo:8750 µg/kg:NOSE,EYE,PUL

    34ZIAG    Toxicology of Drugs and Chemicals ,Deichmann, W.B.,New York, NY.: Academic Press, Inc.,1969,452.
2.    

orl-rat LD50:300 mg/kg

    JMCMAR    Journal of Medicinal Chemistry. 14 (1971),913.
3.    

ipr-rat LD50:142 mg/kg

    ANYAA9    Annals of the New York Academy of Sciences. 107 (1963),1068.
4.    

orl-mus LD50:680 mg/kg

    JMCMAR    Journal of Medicinal Chemistry. 14 (1971),913.
5.    

ipr-mus LD50:290 mg/kg

    THERAP    Therapie. 22 (1967),367.
6.    

scu-mus LD50:380 mg/kg

    BCPCA6    Biochemical Pharmacology. 17 (1968),369.
7.    

ivn-mus LD50:56 mg/kg

    CSLNX*    U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) NX#02420 .
8.    

orl-dog LD50:175 mg/kg

    ANYAA9    Annals of the New York Academy of Sciences. 107 (1963),1068.
9.    

ipr-mky LD50:200 mg/kg

    ANYAA9    Annals of the New York Academy of Sciences. 107 (1963),1068.
10.    

ipr-cat LD50:200 mg/kg

    ANYAA9   

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Wuhan Fortuna Chemical Co., Ltd.
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Rosewell Industry Co., Ltd
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HangZhou Peak Chemical Co.,Ltd
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Tianjin Harmony Technology Development Co., Ltd.
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Wuhan Dahua Weiye Pharmaceutical Co.,Ltd
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Wuhan Senwayer Century chemical Co.,Ltd
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Address: 20#Xudong Street,Wuhan China
Hangzhou Dayangchem Co., Ltd.
Tel:86-571-88938639
Address: 9/F Unit 2 ChangdiTorch Building, 259 #WenSan Road
Wuhan H.X.K Fine Chemicals Co.,LTD
Tel:86-27-59721024
Address: No. 139, hanyang Road, hubei city, Hubei Prov. China 434000

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