Safety
Poison by subcutaneous and intraperitoneal routes. An experimental teratogen. Other experimental reproductive effects. A steroid. When heated to decomposition it emits toxic fumes of F−.
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 276mg/kg (276mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 18, Pg. 474, 1987. | |
| mouse | LD50 | oral | > 10gm/kg (10000mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 18, Pg. 474, 1987. | |
| mouse | LD50 | subcutaneous | 183mg/kg (183mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 18, Pg. 474, 1987. | |
| rabbit | LD50 | subcutaneous | 7600ug/kg (7.6mg/kg) | SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" |
Oyo Yakuri. Pharmacometrics. Vol. 28, Pg. 687, 1984. |
| rat | LD50 | intraperitoneal | 36500ug/kg (36.5mg/kg) | SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" SKIN AND APPENDAGES (SKIN): HAIR: OTHER |
Oyo Yakuri. Pharmacometrics. Vol. 28, Pg. 687, 1984. |
| rat | LD50 | subcutaneous | 26mg/kg (26mg/kg) | SENSE ORGANS AND SPECIAL SENSES: ACRIMATION: EYE SKIN AND APPENDAGES (SKIN): HAIR: OTHER GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" |
Oyo Yakuri. Pharmacometrics. Vol. 28, Pg. 687, 1984. |
| rat | LDLo | oral | 4gm/kg (4000mg/kg) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA SKIN AND APPENDAGES (SKIN): HAIR: OTHER |
Oyo Yakuri. Pharmacometrics. Vol. 28, Pg. 687, 1984. |
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