9H-Thioxanthene-2-sulfonamide,N,N-dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]- cas no:5591-45-7

Name9H-Thioxanthene-2-sulfonamide,N,N-dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-
CAS5591-45-7
SynonymsThioxanthene-2-sulfonamide,N,N-dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]- (7CI,8CI);2-(Dimethylsulfamoyl)-[9-(4-methyl-1-piperazinyl)propylidene]thioxanthene; CP12252-1;N,N-Dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]thioxanthene-2-sulfonamide;NSC 108165; Navan; Navane; Navaron; Orbinamon; P 4657B
EINECS(EC#)227-001-0
Molecular FormulaC23H29 N3 O2 S2
Molecular Weight443.67

refractive index1.643

Safety

Poison by ingestion. Moderately toxic by subcutaneous route. An experimental teratogen. Experimental reproductive effects. Human systemic effects hallucinations, distorted perceptions. When heated to decomposition it emits very toxic fumes of SO_x and NO_x.

1.		orl-man TDLo:3 mg/kg (male 1W pre):REP		JCLPDE    Journal of Clinical Psychiatry. 48 (1987),216.
2.		orl-mus TDLo:180 mg/kg (female 7-12D post):TER		OYYAA2    Oyo Yakuri. Pharmacometrics. 3 (1969),315.
3.		orl-wmn TDLo:300 µg/kg/2D-I:BAH		JCLPDE    Journal of Clinical Psychiatry. 44 (1983),77.
4.		orl-rat LD50:720 mg/kg		NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),455.
5.		scu-rat LD50:2 g/kg		KSRNAM    Kiso to Rinsho. Clinical Report. 3 (1969),709.
6.		orl-mus LD50:400 mg/kg		NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),455.
7.		scu-mus LD50:4 g/kg		KSRNAM    Kiso to Rinsho. Clinical Report. 3 (1969),709.