56-92-8|Histamine dihydrochlorideProducts Supply - Chemical intermediates Network

Histamine dihydrochloride cas no:56-92-8

Synonyms: 2-imidazol-4-ylethylamine dihydrochloride; Histamine-alpha,alpha,??d4?HCl)2; HISTAMINE DICHLORHYDRATE; histamine dihcl; 2-(1H-Imidazol-4-yl)ethylamine dihydrochloride; 2-(4-Imidazolyl)ethylamine dihydrochloride

Identification

NameHistamine dihydrochloride
CAS56-92-8
Synonyms2-imidazol-4-ylethylamine dihydrochloride; Histamine-alpha,alpha,??d4?HCl)2; HISTAMINE DICHLORHYDRATE; histamine dihcl; 2-(1H-Imidazol-4-yl)ethylamine dihydrochloride; 2-(4-Imidazolyl)ethylamine dihydrochloride
EINECS(EC#)200-298-4
Molecular FormulaC5H9N3?2HCl;C5H11Cl2N3
Molecular Weight184.07

Chemical Properties

Appearancewhite powder
storage temp2-8°C

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

HazardclassIRRITANT

Safety Data

Hazard Xi:Irritant;
Risk R42
Safety

Poison by subcutaneous, intravenous, intraperitoneal, and parenteral routes. Moderately toxic by ingestion. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of Cl⁻ and NO_x. See also HISTAMINE.
Hazard Codes: Xn, Xi
Risk Statements:36/37/38-42/43-42-22
22:(Harmful if swallowed)
36/37/38: (Irritating to the eyes piratory system and skin)
42/43:(May cause sensitization by inhalation and skin contact)
42:(May cause sensitization by inhalation)
Safety Statements:22-26-36/37/39-45-37-36/37
22:(Do not breathe dust)
26: (In case of contact with eyes,rinse immediately with plenty of water and seek medical advice)
36/37/39:(Wear suitable protective clothing, gloves and eye/face protection)
45:(In case of accident or if you feel unwell, seek medical advice immediately (show label where possible))
37:(Wear suitable gloves)
36/37:(Wear suitable protective clothing and gloves)
WGK Germany:2
RTECS:MS1575000
F:1-8-9
Hazard Note:Irritant

Toxicity

1.	orl-mus LD50:2534 mg/kg	ARTODN Archives of Toxicology. 2 (1979),371.
2.	ipr-mus LD50:184 mg/kg	YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. 97 (1977),1117.
3.	scu-mus LDLo:1300 mg/kg	AEPPAE Naunyn-Schmiedeberg’s Archiv fuer Experimentelle Pathologie und Pharmakologie. 166 (1932),437.
4.	ivn-mus LD50:370 mg/kg	ATSUDG Archives of Toxicology, Supplement. 2 (1979),371.
5.	ipr-rbt LDLo:200 mg/kg	JIDIAQ Journal of Infectious Diseases. 42 (1928),473.
6.	ipr-gpg LD50:4602 µg/kg	JPETAB Journal of Pharmacology and Experimental Therapeutics. 77 (1943),54.
7.	scu-gpg LD50:1250 µg/kg	TXAPA9 Toxicology and Applied Pharmacology. 8 (1966),339.
8.	ivn-gpg LD50:294 µg/kg	JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. 33 (1944),80.
9.	par-gpg LDLo:570 µg/kg	AEPPAE Naunyn-Schmiedeberg’s Archiv fuer Experimentelle Pathologie und Pharmakologie. 211 (1950),328.

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Histamine dihydrochloride cas no:56-92-8

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