562-10-7|Doxylamine succinateProducts Supply - Chemical intermediates Network

Doxylamine succinate cas no:562-10-7

Synonyms: 2-[[.alpha.-(2-Dimethylamino)ethoxy]-.alpha.-methylbenzyl]pyridine succinate;2-Dimethylaminoethoxyphenylmethyl-2-picoline succinate (1:1);butanedioic acid; N,N-dimethyl-2-(1-phenyl-1-pyridin-2-yl-ethoxy)ethanamine;Doxylamine succinate (1:1);Unisom;Phenyl2-pyridylmethyl-beta-N,N-dimethylaminoethyl ether succinate;(Dimethylamino)ethoxy-methyl-benzyl-pyridine succinate;Pyridine, 2-[.alpha.-[2- (dimethylamino)ethoxy]-.alpha.-methylbenzyl]-, succinate (1:1);Doxylamine hydrogen succinate;Gittalun;Hoggar N;Pyridine, 2-(alpha-(2-(dimethylamino)ethoxy)-alpha-methylbenzyl)-, succinate (1:1);2-Dimethylaminoethoxyphenylmethyl-2-picoline succinate;Butanedioic acid, compd. with N, N-dimethyl-2-[1-phenyl-1- (2-pyridinyl)ethoxy]ethanamine (1:1);

Identification

NameDoxylamine succinate
CAS562-10-7
Synonyms2-[[.alpha.-(2-Dimethylamino)ethoxy]-.alpha.-methylbenzyl]pyridine succinate;2-Dimethylaminoethoxyphenylmethyl-2-picoline succinate (1:1);butanedioic acid; N,N-dimethyl-2-(1-phenyl-1-pyridin-2-yl-ethoxy)ethanamine;Doxylamine succinate (1:1);Unisom;Phenyl2-pyridylmethyl-beta-N,N-dimethylaminoethyl ether succinate;(Dimethylamino)ethoxy-methyl-benzyl-pyridine succinate;Pyridine, 2-[.alpha.-[2- (dimethylamino)ethoxy]-.alpha.-methylbenzyl]-, succinate (1:1);Doxylamine hydrogen succinate;Gittalun;Hoggar N;Pyridine, 2-(alpha-(2-(dimethylamino)ethoxy)-alpha-methylbenzyl)-, succinate (1:1);2-Dimethylaminoethoxyphenylmethyl-2-picoline succinate;Butanedioic acid, compd. with N, N-dimethyl-2-[1-phenyl-1- (2-pyridinyl)ethoxy]ethanamine (1:1);
EINECS(EC#)209-228-7
Molecular FormulaC₁₇H₂₂N₂O^.C₄H₆O₄
Molecular Weight388.45742

Chemical Properties

Appearancewhite to light cream powder
storage tempRefrigerator

Safety Data

Hazard Xn: Harmful;
Risk R22;R36/37/38
Safety

Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. Mutation data reported. Questionable carcinogen with experimental carcinogenic data. When heated to decomposition it emits toxic fumes of NO_x.

Hazard Codes of Doxylamine succinate (CAS NO.562-10-7): Harmful Xn
Risk Statements:
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements:
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37:Wear suitable protective clothing and gloves.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intravenous	62mg/kg (62mg/kg)		Journal of Laboratory and Clinical Medicine. Vol. 33, Pg. 325, 1948.
mouse	LD50	oral	470mg/kg (470mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Journal of Laboratory and Clinical Medicine. Vol. 33, Pg. 325, 1948.
mouse	LD50	subcutaneous	460mg/kg (460mg/kg)		Journal of Laboratory and Clinical Medicine. Vol. 33, Pg. 325, 1948.
rabbit	LD50	intravenous	49mg/kg (49mg/kg)		Journal of Laboratory and Clinical Medicine. Vol. 33, Pg. 325, 1948.
rabbit	LD50	oral	250mg/kg (250mg/kg)		Journal of Laboratory and Clinical Medicine. Vol. 33, Pg. 325, 1948.
rat	LD50	subcutaneous	440mg/kg (440mg/kg)		Journal of Laboratory and Clinical Medicine. Vol. 33, Pg. 325, 1948.
rat	LDLo	oral	600mg/kg (600mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: FOOD INTAKE (ANIMAL)	Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 37, Pg. 311, 1948.

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Doxylamine succinate cas no:562-10-7

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