56238-63-2|Cefuroxime sodiumProducts Supply - Chemical intermediates Network

Cefuroxime sodium cas no:56238-63-2

Synonyms: 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,3-[[(aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-furanyl(methoxyimino)acetyl]amino]-8-oxo-,monosodium salt, (6R,7R)- (9CI);5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,3-[[(aminocarbonyl)oxy]methyl]-7-[[2-furanyl(methoxyimino)acetyl]amino]-8-oxo-,monosodium salt, [6R-[6a,7b(Z)]]-;640/359;Biociclin;Bioxima;Cefamar;Cefumax;Cefurex;Cefurin;Curocef;Curoxim;Duxima;Ipacef;Kefurox;Lampsporin;Medoxim;Novocef;Spectrazol;Ultroxim;Zinacef;

Identification

NameCefuroxime sodium
CAS56238-63-2
Synonyms5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,3-[[(aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-furanyl(methoxyimino)acetyl]amino]-8-oxo-,monosodium salt, (6R,7R)- (9CI);5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,3-[[(aminocarbonyl)oxy]methyl]-7-[[2-furanyl(methoxyimino)acetyl]amino]-8-oxo-,monosodium salt, [6R-[6a,7b(Z)]]-;640/359;Biociclin;Bioxima;Cefamar;Cefumax;Cefurex;Cefurin;Curocef;Curoxim;Duxima;Ipacef;Kefurox;Lampsporin;Medoxim;Novocef;Spectrazol;Ultroxim;Zinacef;
EINECS(EC#)260-073-1
Molecular FormulaC₁₆H₁₅N₄NaO₈S
Molecular Weight446.37

Chemical Properties

AppearanceWhite Crystalline Solid
storage temp2-8°C

Safety Data

Hazard Xn: Harmful;
Risk R42/43
Safety

Safety Information of Cefuroxime sodium (CAS NO.56238-63-2):
Hazard Codes:? Harmful Xn
Risk Statements: 42/43-36/37/38-20/21/22?
R42/43:May cause sensitization by inhalation and skin contact.?
R36/37/38:Irritating to eyes, respiratory system and skin.?
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 22-36/37-45-36-26?
S22:Do not breathe dust.?
S36/37:Wear suitable protective clothing and gloves.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S36:Wear suitable protective clothing.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: 2
RTECS: XI0330000
Moderately toxic by intravenous route. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of SO_x, NO_x, and Na₂O.

HS Code 29419000

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	> 1500mg/kg (1500mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 13, Pg. 349, 1982.
mouse	LD50	intramuscular	> 2gm/kg (2000mg/kg)	?	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 24, Pg. 261, 1982.
mouse	LD50	intraperitoneal	> 10gm/kg (10000mg/kg)	?	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 24, Pg. 261, 1982.
mouse	LD50	intravenous	10400mg/kg (10400mg/kg)	?	Toxicology. Vol. 13, Pg. 1, 1979.
mouse	LD50	oral	> 10gm/kg (10000mg/kg)	?	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 24, Pg. 261, 1982.
mouse	LD50	subcutaneous	> 10gm/kg (10000mg/kg)	?	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 24, Pg. 261, 1982.
rabbit	LD50	intramuscular	> 300mg/kg (300mg/kg)	?	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 24, Pg. 261, 1982.
rabbit	LD50	intravenous	> 1500mg/kg (1500mg/kg)	?	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 24, Pg. 261, 1982.
rat	LD50	intramuscular	> 2gm/kg (2000mg/kg)	?	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 24, Pg. 261, 1982.
rat	LD50	intraperitoneal	10gm/kg (10000mg/kg)	KIDNEY, URETER, AND BLADDER: OTHER CHANGES	Chemotherapy Vol. 27(Suppl,
rat	LD50	intravenous	4gm/kg (4000mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Toxicology. Vol. 13, Pg. 1, 1979.
rat	LD50	oral	> 10gm/kg (10000mg/kg)	?	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 24, Pg. 261, 1982.
rat	LD50	subcutaneous	> 10gm/kg (10000mg/kg)	?	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 24, Pg. 261, 1982.

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Cefuroxime sodium cas no:56238-63-2

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