56392-17-7|Metoprolol tartrateProducts Supply - Chemical intermediates Network

Metoprolol tartrate cas no:56392-17-7

Synonyms: Metoprolol-(+,-) (+)-tartrate salt;2-Propanol,1-[4-(2-methoxyethyl)phenoxy]-3- [(1-methylethyl)amino]-,(2R,3R)-2,3- dihydroxybutanedioate (2:1) (salt);Betaloc;Beloc;Seloken;Lopressor;Metoprolol tartrate (JAN/USP);Lopresor;(2R,3R)-2,3-dihydroxybutanedioic acid; 1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol;Prestwick_1009;2,3-dihydroxybutanedioic acid; 1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol;Lopressor (TN);Metoprolol tartaric acid;

Identification

NameMetoprolol tartrate
CAS56392-17-7
SynonymsMetoprolol-(+,-) (+)-tartrate salt;2-Propanol,1-[4-(2-methoxyethyl)phenoxy]-3- [(1-methylethyl)amino]-,(2R,3R)-2,3- dihydroxybutanedioate (2:1) (salt);Betaloc;Beloc;Seloken;Lopressor;Metoprolol tartrate (JAN/USP);Lopresor;(2R,3R)-2,3-dihydroxybutanedioic acid; 1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol;Prestwick_1009;2,3-dihydroxybutanedioic acid; 1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol;Lopressor (TN);Metoprolol tartaric acid;
EINECS(EC#)260-148-9
Molecular Formula2(C₁₅H₂₅NO₃)^.(C₄H₆O₆)
Molecular Weight684.81464

Chemical Properties

Appearancewhite to off-white / powder
storage tempKeep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Safety Data

Safety

RTECS of Metoprolol tartrate (CAS NO.56392-17-7): UB7450100

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	oral	1090mg/kg (1090mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 14, Pg. 297, 1983.
human	TDLo	oral	160mg/kg (160mg/kg)	CARDIAC: PULSE RATE VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION LUNGS, THORAX, OR RESPIRATION: CYANOSIS	British Medical Journal. Vol. 1, Pg. 222, 1976.
mouse	LD50	intraperitoneal	202mg/kg (202mg/kg)		Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 24, Pg. 2439, 1982.
mouse	LD50	intravenous	84mg/kg (84mg/kg)		Drugs in Japan Vol. -, Pg. 614, 1995.
mouse	LD50	oral	1500mg/kg (1500mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Kiso to Rinsho. Clinical Report. Vol. 13, Pg. 2839, 1979.
mouse	LD50	subcutaneous	510mg/kg (510mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Kiso to Rinsho. Clinical Report. Vol. 13, Pg. 2839, 1979.
rabbit	LD50	intravenous	28700ug/kg (28.7mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 14, Pg. 297, 1983.
rabbit	LD50	oral	604mg/kg (604mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 14, Pg. 297, 1983.
rat	LD50	intraperitoneal	219mg/kg (219mg/kg)		Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 24, Pg. 2439, 1982.
rat	LD50	intravenous	90mg/kg (90mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Kiso to Rinsho. Clinical Report. Vol. 13, Pg. 2839, 1979.
rat	LD50	oral	5500mg/kg (5500mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Kiso to Rinsho. Clinical Report. Vol. 13, Pg. 2839, 1979.
rat	LD50	subcutaneous	1150mg/kg (1150mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Kiso to Rinsho. Clinical Report. Vol. 13, Pg. 2839, 1979.

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Metoprolol tartrate cas no:56392-17-7

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