564-25-0|2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,(4S,4aR,5S,5aR,6R,12aS)-Products Supply

2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,(4S,4aR,5S,5aR,6R,12aS)- cas no:564-25-0

Synonyms: 2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-(6CI,8CI);2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,[4S-(4a,4aa,5a,5aa,6a,12aa)]-;4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide;5-Hydroxy-a-6-deoxytetracycline;6-Deoxy-5-hydroxytetracycline;6-Deoxyoxytetracycline;Dentistar;Deoxymykoin;Dotur;Doximal;Doxinyl;Doxivetin;Doxy RW;Doxy-Gel;Doxycen;Doxycycline;GS 3065;Hydramycin;Liviatin;Medeomycin;Monodox;Oxytetracycline, 6-deoxy-;Pulmodox;Ronaxan;Tolexine;Unidox;Vibramycin;Vibramycine;Vibraveineuse;a-6-Deoxy-5-hydroxytetracycline;a-Doxycycline;

Identification

Name2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,(4S,4aR,5S,5aR,6R,12aS)-
CAS564-25-0
Synonyms2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-(6CI,8CI);2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,[4S-(4a,4aa,5a,5aa,6a,12aa)]-;4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide;5-Hydroxy-a-6-deoxytetracycline;6-Deoxy-5-hydroxytetracycline;6-Deoxyoxytetracycline;Dentistar;Deoxymykoin;Dotur;Doximal;Doxinyl;Doxivetin;Doxy RW;Doxy-Gel;Doxycen;Doxycycline;GS 3065;Hydramycin;Liviatin;Medeomycin;Monodox;Oxytetracycline, 6-deoxy-;Pulmodox;Ronaxan;Tolexine;Unidox;Vibramycin;Vibramycine;Vibraveineuse;a-6-Deoxy-5-hydroxytetracycline;a-Doxycycline;
EINECS(EC#)209-271-1
Molecular FormulaC₂₂H₂₄N₂O₈
Molecular Weight444.44

Chemical Properties

Appearanceyellow crystal powder
refractive index1.737
storage tempstore in a tightly closed container.

Safety Data

Safety

Moderately toxic by ingestion and intraperitoneal routes. An experimental teratogen. Human mutation data reported. When heated to decomposition it emits toxic fumes of NO_x.

Toxicity

rganism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	> 100mg/kg (100mg/kg)	?	Pharmacological and Biochemical Properties of Drug Substances. Vol. 2, Pg. 305, 1979.
dog	LD50	oral	> 500mg/kg (500mg/kg)	?	Pharmacological and Biochemical Properties of Drug Substances. Vol. 2, Pg. 305, 1979.
mouse	LD50	intraperitoneal	410mg/kg (410mg/kg)	?	Giornale Italiano di Chemioterapia. Italian Journal of Chemotherapy. Vol. 17, Pg. 276, 1970.
mouse	LD50	intravenous	241mg/kg (241mg/kg)	?	Pharmacological and Biochemical Properties of Drug Substances. Vol. 2, Pg. 305, 1979.
mouse	LD50	oral	1870mg/kg (1870mg/kg)	?	Giornale Italiano di Chemioterapia. Italian Journal of Chemotherapy. Vol. 17, Pg. 276, 1970.
rat	LD50	intraperitoneal	378mg/kg (378mg/kg)	?	Therapie. Vol. 23, Pg. 575, 1968.
rat	LD50	intravenous	228mg/kg (228mg/kg)	?	Pharmacological and Biochemical Properties of Drug Substances. Vol. 2, Pg. 305, 1979.
rat	LD50	oral	> 2gm/kg (2000mg/kg)	?	Pharmacological and Biochemical Properties of Drug Substances. Vol. 2, Pg. 305, 1979.
women	TDLo	oral	68mg/kg/24D-I (68mg/kg)	MUSCULOSKELETAL: JOINTS	Postgraduate Medical Journal. Vol. 67, Pg. 313, 1991.

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HELM AG: Tel:+49-40-2375-0; Address: HELM AG, Nordkanalstrasse 28,D-20097 Hamburg, Germany

Suntin MediPharma Co. Ltd.: Tel:+86 755 8386 5062 ; +852 2690 9351; Address: RM.2501-2502, 25/F., Convention & Exhibition Times Center, 3008 Yitian RD., Shenzhen China.

Chongqing Perfect Import & Export Co., Ltd.: Tel:; Address: 14/f Tower A,Digital Building, 26 Ou Street Xinglong Road,Jiangbei District Chongqing,China

Praevideo LLC: Tel:+36-(1)-347-0332; Address: Baross U. 46, Budapest H 1192,

Micro Orgo Chem: Tel:+91-(22)-24448834; Address: 28, Lohar Chawl, Mahim, Mumbai, Maharashtra 400016,

Hovione S.A.: Tel:+351-(21)-982 9000; Address: Sete Casas, Loures 2674-506,

Suzhou Howsine Biological Technology Co., Ltd.: Tel:+86-(512)-68128052; Address: No, 485 Panxu Road, Suzhou, Jiangsu 215007,

Yangzhou Pharmaceutical Co., Ltd.: Tel:+86-(514)-87829985/87812867; Address: 7, South Wenfeng Road, Yangzhou, Jiangsu 225009,

Tecoland Corporation: Tel:+1-(732)-603-9577; Address: 100 Menlo Park Drive, Suite 316, Edison, New Jersey 08837-2428,

Billiken International Holding Ltd.: Tel:+86-(755)-2640-8073, 2640-8072; Address: Unit 04, 26F, Yihai Square East, No.90 Chuangye Road, Shenzhen, Guangdong,

Choriway International Trade Co., Ltd.: Tel:+86-(510)-82606408/82700303; Address: Room 716, No. 126. Quanchang Road, Wuxi, Jigansu 214043,

Ronas Chemicals Ind. Co., Ltd.: Tel:+86-(28)-86082869; Address: Rome International Plaza,Room 09A,19th Floor,NO.210,West Yulong Street, Chengdu, Qingyang District, Sichuan 610072,

Alfa Chem: Tel:+1-(516)-504-0059, 800-375-6869; Address: 2 Harbor Way, Kings Point, New York 11024,

Steamline Industries Ltd.: Tel:+91-(22)-40999700, 9833720865; Address: 901/904 Jagdamba Commercial Complex A/2, Near Movitime Theatre, Link Road, Malad (W), Mumbai, Maharashtra 400064,

King Tang Chemical Industry Group Co.,Ltd: Tel:86 519 8230 9998; Address: 7F, New Century Building, NO. 209 East Ave, Jintan, Changzhou 213200, Jiangsu, P.R.China

2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,(4S,4aR,5S,5aR,6R,12aS)- cas no:564-25-0

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