PHENDIMETRAZINE TARTRATE cas no:569-59-5

NamePHENDIMETRAZINE TARTRATE
CAS569-59-5
Synonymsphenindamine tartrate
EINECS(EC#)209-320-7
Molecular FormulaC₁₉H₁₉N . C₄H₆O₆
Molecular Weight411.49

Safety

Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. An antihistamine. When heated to decomposition it emits toxic fumes of NO_x.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LD50	intravenous	24500ug/kg (24.5mg/kg)		Archives Internationales de Pharmacodynamie et de Therapie. Vol. 113, Pg. 313, 1958.
mouse	LD50	intraperitoneal	88mg/kg (88mg/kg)	cardiac: other changes	Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 291, 1952.
mouse	LD50	intravenous	18mg/kg (18mg/kg)		U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#03034,
mouse	LD50	oral	265mg/kg (265mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 291, 1952.
rabbit	LD50	oral	577mg/kg (577mg/kg)		"Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969Vol. -, Pg. 91, 1969.
rat	LD50	oral	280mg/kg (280mg/kg)		"Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969Vol. -, Pg. 91, 1969.
rat	LDLo	subcutaneous	200mg/kg (200mg/kg)	behavioral: tremor behavioral: excitement	Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 144, Pg. 887, 1950.