Piperazine,1-[(4-chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]- cas no:569-65-3
Synonyms: Piperazine,1-(p-chloro-a-phenylbenzyl)-4-(m-methylbenzyl)-(6CI,8CI);1-(p-Chlorobenzhydryl)-4-(m-methylbenzyl)diethylenediamine;Ancolan;Bonine;Histametizyne;Meclizine;NSC 169189;Navicalm;Neo-Istafene;Parachloramine;Postafene;Ravelon;Sabari;Suprimal;U.C.B. 5062;Vomisseis;
NamePiperazine,1-[(4-chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]-
CAS569-65-3
SynonymsPiperazine,1-(p-chloro-a-phenylbenzyl)-4-(m-methylbenzyl)-(6CI,8CI);1-(p-Chlorobenzhydryl)-4-(m-methylbenzyl)diethylenediamine;Ancolan;Bonine;Histametizyne;Meclizine;NSC 169189;Navicalm;Neo-Istafene;Parachloramine;Postafene;Ravelon;Sabari;Suprimal;U.C.B. 5062;Vomisseis;
EINECS(EC#)209-323-3
Molecular FormulaC25H27ClN2
Molecular Weight390.94828
storage tempKeep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Hazard Xn:;
Risk R22;R36/37/38
Safety
A poison by intravenous route. Moderate toxicity by ingestion and intramuscular routes. Human reproductive effects by an unspecified route: reduced viability of newborn. Experimental teratogenic and reproductive effects. An antihistamine. When heated to decomposition it emits very toxic fumes of Cl− and NOx.
Attention:
1. Storage: Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
2. Handling: All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intramuscular |
625mg/kg (625mg/kg) |
|
Compilation of LD50 Values of New Drugs. |
| mouse |
LD50 |
oral |
1650mg/kg (1650mg/kg) |
|
Compilation of LD50 Values of New Drugs. |
| rat |
LD50 |
oral |
1750mg/kg (1750mg/kg) |
|
Proceedings of the European Society for the Study of Drug Toxicity. Vol. 9, Pg. 134, 1968. |
