Aziridine,1,1',1''-phosphinylidynetris[2-methyl- cas no:57-39-6
Synonyms: Phosphineoxide, tris(2-methyl-1-aziridinyl)- (6CI,8CI);EMT 50003;MAPO;MAPO(chemosterilant);Metapa;Metapoxide;Metepa;Methaphoxide;Methyl aphoxide;NSC 54054;Trimethylaziridinylphosphine oxide;Tris(1,2-propylene)phosphoramide;Tris(2-methylaziridinyl)phosphine oxide;Tris(methylaziridinyl)phosphine oxide;
NameAziridine,1,1',1''-phosphinylidynetris[2-methyl-
CAS57-39-6
SynonymsPhosphineoxide, tris(2-methyl-1-aziridinyl)- (6CI,8CI);EMT 50003;MAPO;MAPO(chemosterilant);Metapa;Metapoxide;Metepa;Methaphoxide;Methyl aphoxide;NSC 54054;Trimethylaziridinylphosphine oxide;Tris(1,2-propylene)phosphoramide;Tris(2-methylaziridinyl)phosphine oxide;Tris(methylaziridinyl)phosphine oxide;
EINECS(EC#)200-326-5
Molecular FormulaC9H18N3OP
Molecular Weight215.23
AppearanceWater white to straw coloured viscous liquid
storage tempStore in a cool, dry location - 18 C or below at all times.
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety
Poison by ingestion, skin contact, intraperitoneal, and subcutaneous routes. Experimental teratogenic and reproductive effects. Questionable carcinogen with experimental carcinogenic data. Animal experiments suggest cholinesterase inhibition, possibly due to metabolic products of this material in the body. When heated to decomposition it emits very toxic fumes of NOx and POx.
Safety information of 1-Bis(2-methylaziridin-1-yl)phosphoryl-2-methylaziridine (57-39-6):
RIDADR? 2810
HazardClass? 6.1(b)
PackingGroup? III
| 1. |
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dni-esc 10?mmol/L
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IJEBA6 ?? Indian Journal of Experimental Biology. 22 (1984),453. |
| 2. |
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cyt-hmn:lym 20?mg/L
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SOGEBZ ?? Soviet Genetics. Translation of GNKAA5. 8 (1972),783. |
| 3. |
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orl-rat LD50:136?mg/kg
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TXAPA9 ?? Toxicology and Applied Pharmacology. 14 (1969),515. |
| 4. |
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skn-rat LD50:183?mg/kg
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BWHOA6 ?? Bulletin of the World Health Organization. 31 (1964),737. |
| 5. |
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orl-mus LD50:292?mg/kg
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INHEAO ?? Industrial Health. 8 (1970),54. |
| 6. |
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skn-mus LD50:375?mg/kg
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INHEAO ?? Industrial Health. 8 (1970),54. |
| 7. |
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ipr-mus LDLo:3125?μg/kg
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TXAPA9 ?? Toxicology and Applied Pharmacology. 23 (1972),288. |
| 8. |
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scu-mus LD50:140?mg/kg
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INHEAO ?? Industrial Health. 8 (1970),54. |
| 9. |
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orl-ckn LD50:329?mg/kg
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TXAPA9 ?? Toxicology and Applied Pharmacology. 16 (1970),100. |
| 10. |
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orl-dom LDLo:50?mg/kg
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ANYAA9 ?? Annals of the New York Academy of Sciences. 111 (1964),715. |
