4,7-Methano-1H-indene,1,2,4,5,6,7,8,8-octachloro-2,3,3a,4,7,7a-hexahydro- cas no:57-74-9

Name4,7-Methano-1H-indene,1,2,4,5,6,7,8,8-octachloro-2,3,3a,4,7,7a-hexahydro-
CAS57-74-9
Synonyms4,7-Methanoindan,1,2,4,5,6,7,8,8-octachloro-3a,4,7,7a-tetrahydro- (6CI,8CI); 1,2,4,5,6,7,10,10-Octachloro-4,7,8,9-tetrahydro-4,7-endomethyleneindane;1,2,4,5,6,7,10,10-Octachloro-4,7,8,9-tetrahydro-4,7-methyleneindane;1,2,4,5,6,7,8,8-Octachloro-4,7-methano-3a,4,7,7a-tetrahydroindane; CD 68;Chlorindan; Cortilan-neu; Dowchlor; ENT 9932; HCS 3260; M 140; NSC 8931;Octachloro-4,7-methanotetrahydroindane; Oktaterr; Tat Chlor 4; Toxichlor
EINECS(EC#)200-349-0
Molecular FormulaC10H6 Cl8
Molecular Weight409.7814

Appearanceoff-white powder
refractive index1.604
storage temp0-6°C

Hazardclass6.1(b)

Hazard An animal carcinogen. Toxic by ingestion, inhalation, and skin absorption. TLV: 0.5 mg/m3.
Risk 21/22-40-50/53-36/37/38-11-39/23/24/25-23/24/25
Safety

Suspected carcinogen. A poison by ingestion. Moderately toxic by skin contact. Experimental reproductive effects. Mutation data reported.
Hazard Codes:
Xn
N
Xi
F
T
Risk Statements:
R21/22:Harmful in contact with skin and if swallowed. 
R40:Limited evidence of a carcinogenic effect. 
R50/53:Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. 
R36/37/38:Irritating to eyes, respiratory system and skin. 
R11:Highly flammable. 
R39/23/24/25:Danger of very serious irreversible effects and toxic by inhalation, in contact with skin and if swallowed. 
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.
Safety Statements:
S36/37:Wear suitable protective clothing and gloves. 
S60:This material and its container must be disposed of as hazardous waste. 
S61:Avoid release to the environment. Refer to special instructions / safety data sheets. 
S36:Wear suitable protective clothing. 
S33:Take precautionary measures against static discharges. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S16:Keep away from sources of ignition. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S7:Keep container tightly closed.
RIDADR: 2995
RTECS: PB9800000
HazardClass: 6.1(b)
PackingGroup: II

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LC50	inhalation	100mg/m3/4H (100mg/m3)	behavioral: somnolence (general depressed activity) behavioral: convulsions or effect on seizure threshold behavioral: excitement	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 8(4), Pg. 30, 1964.
chicken	LD50	oral	220mg/kg (220mg/kg)		Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 226, 1966.
domestic animals - goat/sheep	LD50	oral	50mg/kg (50mg/kg)		Yakkyoku. Pharmacy. Vol. 32, Pg. 471, 1981.
duck	LD50	oral	1200mg/kg (1200mg/kg)		Down to Earth. Vol. 35, Pg. 25, 1979.
hamster	LD50	oral	1720mg/kg (1720mg/kg)		European Journal of Toxicology and Environmental Hygiene. Vol. 7, Pg. 159, 1974.
human	LDLo	oral	29mg/kg (29mg/kg)	liver: fatty liver degeration	"Clinical Memoranda on Economic Poisons," U.S. Dept. HEW, Public Health Service, Communicable Disease Center, Atlanta, GA, 1956Vol. -, Pg. 1, 1956.
human	LDLo	skin	428mg/kg (428mg/kg)	behavioral: tremor behavioral: convulsions or effect on seizure threshold behavioral: ataxia	"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 648, 1969.
mammal (species unspecified)	LC50	inhalation	> 20gm/m3/4H (20000mg/m3)		Pesticide Manual. Vol. 9, Pg. 139, 1991.
mammal (species unspecified)	LD50	oral	180mg/kg (180mg/kg)		Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 226, 1966.
man	LDLo	unreported	118mg/kg (118mg/kg)		"Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970.
man	TDLo	oral	3071ug/kg (3.071mg/kg)	behavioral: coma lungs, thorax, or respiration: dyspnea gastrointestinal: nausea or vomiting	Journal of Toxicology, Clinical Toxicology. Vol. 20, Pg. 291, 1983.
mouse	LD50	intravenous	100mg/kg (100mg/kg)		U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#04876,
mouse	LD50	oral	145mg/kg (145mg/kg)		Agricultural Research Service, USDA Information Memorandum. Vol. 20, Pg. 19, 1966.
mouse	LDLo	intraperitoneal	240mg/kg (240mg/kg)		Toxicology and Applied Pharmacology. Vol. 23, Pg. 288, 1972.
rabbit	LD50	oral	100mg/kg (100mg/kg)		Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 226, 1966.
rabbit	LD50	skin	780mg/kg (780mg/kg)		"Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel," Perkow, W., Berlin, Verlag Paul Parey, 1971-1976Vol. -, Pg. -, 1971/1976.
rabbit	LDLo	intravenous	10mg/kg (10mg/kg)		Archives of Industrial Hygiene and Occupational Medicine. Vol. 1, Pg. 13, 1950.
rat	LD50	intraperitoneal	343mg/kg (343mg/kg)		Toxicology and Applied Pharmacology. Vol. 32, Pg. 443, 1975.
rat	LD50	oral	200mg/kg (200mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 17, Pg. 614, 1967.
rat	LD50	skin	690mg/kg (690mg/kg)		Journal of the American Veterinary Medical Association. Vol. 157, Pg. 1835, 1970.
women	LDLo	oral	120ug/kg (0.12mg/kg)	behavioral: convulsions or effect on seizure threshold behavioral: excitement gastrointestinal: gastritis	"Clinical Memoranda on Economic Poisons," U.S. Dept. HEW, Public Health Service, Communicable Disease Center, Atlanta, GA, 1956Vol. -, Pg. 1, 1956.