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Estra-1,3,5(10)-triene-3,17-diol,(17a)- cas no:57-91-0

Synonyms: 17a-Estradiol (8CI);1,3,5-Estratriene-3,17a-diol;13b-Methyl-1,3,5(10)-gonatriene-3,17a-diol;17-Epiestradiol;17a-Oestradiol;3,17-Dihydroxyestratriene;3,17a-Dihydroxyestra-1,3,5(10)-triene;3,17a-Dihydroxyoestra-1,3,5(10)-triene;Alfatradiol;Epiestrol;Estra-1,3,5(10)-triene-3,17a-diol;NSC 20293;Oestra-1,3,5(10)-triene-3,17a-diol;a-Estradiol;

Identification
NameEstra-1,3,5(10)-triene-3,17-diol,(17a)-
CAS57-91-0
Synonyms17a-Estradiol (8CI);1,3,5-Estratriene-3,17a-diol;13b-Methyl-1,3,5(10)-gonatriene-3,17a-diol;17-Epiestradiol;17a-Oestradiol;3,17-Dihydroxyestratriene;3,17a-Dihydroxyestra-1,3,5(10)-triene;3,17a-Dihydroxyoestra-1,3,5(10)-triene;Alfatradiol;Epiestrol;Estra-1,3,5(10)-triene-3,17a-diol;NSC 20293;Oestra-1,3,5(10)-triene-3,17a-diol;a-Estradiol;
EINECS(EC#)200-354-8
Molecular FormulaC18H24O2
Molecular Weight272.38196
Chemical Properties
Appearancepowder
refractive index1.599
storage temp0-6°C
Safety Data

Hazard Xn: Harmful;
Risk R40;R48
Safety

Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data. Human mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes. A steroid. See also ESTRADIOL.
Safety Information about (8R,9S,13S,14S,17R)-13-Methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol (57-91-0):  
Hazard Codes: 
T:       Xn: 
Risk Statements about (8R,9S,13S,14S,17R)-13-Methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol (57-91-0):   
R45: May cause cancer.
R40: Limited evidence of a carcinogenic effect.
R48: Danger of serious damage to health by prolonged exposure.
Safety Statements about (8R,9S,13S,14S,17R)-13-Methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol (57-91-0):   
S22: Do not breathe dust.
S24/25: Avoid contact with skin and eyes.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible).
S53: Avoid exposure - obtain special instruction before use.
F8: Photosensitive.
F10: Keep under argon.
RIDADR: UN 2811 6.1/PG 2
WGK Germany: 3
RTECS: KG3750000


Toxicity
1.    

dni-hmn:oth 100 mg/L

    JTEHD6    Journal of Toxicology and Environmental Health. 10 (1982),143.
2.    

imp-gpg TD:3 mg/kg:ETA,REP

    RBBIAL    Revista Brasileira de Biologia. 5 (1945),1.

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