Piperazine,1-cyclohexyl-4-(1,2-diphenylethyl)-, hydrochloride (1:2) cas no:57314-55-3

Synonyms: Piperazine,1-cyclohexyl-4-(1,2-diphenylethyl)-, dihydrochloride (9CI); Piperazine, 1-cyclohexyl-4-(1,2-diphenylethyl)-,dihydrochloride, (?à)-; (?à)-1-Cyclohexyl-4-(1,2-diphenylethyl)piperazinedihydrochloride; NSC 299236

Identification

NamePiperazine,1-cyclohexyl-4-(1,2-diphenylethyl)-, hydrochloride (1:2)
CAS57314-55-3
SynonymsPiperazine,1-cyclohexyl-4-(1,2-diphenylethyl)-, dihydrochloride (9CI); Piperazine, 1-cyclohexyl-4-(1,2-diphenylethyl)-,dihydrochloride, (?à)-; (?à)-1-Cyclohexyl-4-(1,2-diphenylethyl)piperazinedihydrochloride; NSC 299236
Molecular FormulaC24H32 N2 . 2 Cl H
Molecular Weight421.50

Safety Data

Safety

Poison by ingestion, subcutaneous, intravenous and intraperitoneal routes. When heated to decomposition Piperazine, 1-cyclohexyl-4-(1,2-diphenylethyl)-, dihydrochloride, (+-)- (CAS NO.57314-55-3) emits toxic fumes of NO_x and HCl.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	58400ug/kg (58.4mg/kg)	BEHAVIORAL: REGIDITY BEHAVIORAL: ANTIPSYCHOTIC LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 221, Pg. 105, 1976.
mouse	LD50	intravenous	17800ug/kg (17.8mg/kg)	BEHAVIORAL: REGIDITY LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: ANTIPSYCHOTIC	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 221, Pg. 105, 1976.
mouse	LD50	oral	329mg/kg (329mg/kg)	BEHAVIORAL: REGIDITY BEHAVIORAL: ANTIPSYCHOTIC LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 221, Pg. 105, 1976.
mouse	LD50	subcutaneous	743mg/kg (743mg/kg)	BEHAVIORAL: REGIDITY BEHAVIORAL: ANTIPSYCHOTIC LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 221, Pg. 105, 1976.
rat	LD50	intravenous	7800ug/kg (7.8mg/kg)	BEHAVIORAL: REGIDITY BEHAVIORAL: ANTIPSYCHOTIC LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 221, Pg. 105, 1976.
rat	LD50	oral	150mg/kg (150mg/kg)	BEHAVIORAL: REGIDITY BEHAVIORAL: ANTIPSYCHOTIC LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 221, Pg. 105, 1976.
rat	LD50	subcutaneous	136mg/kg (136mg/kg)	BEHAVIORAL: REGIDITY BEHAVIORAL: ANTIPSYCHOTIC LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 221, Pg. 105, 1976.

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