Pheniodol cas no:577-91-3

NamePheniodol
CAS577-91-3
SynonymsIodoalphionic Acid;Pheniodol;Iodoalphionic;PHENIODOL(IODOALPHIONIC ACID);Biliognost;Biliselectan;Dikol;Iodobil
EINECS(EC#)209-417-4
Molecular FormulaC15H12I2O3
Molecular Weight494.057

refractive index1.724

Safety

Poison by intravenous route. Moderately toxic by ingestion, intraperitoneal, and subcutaneous routes. When Pheniodol (CAS NO.577-91-3) is heated to decomposition, it emits very toxic fumes of I⁻.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LDLo	intravenous	100mg/kg (100mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Journal of Laboratory and Clinical Medicine. Vol. 27, Pg. 1376, 1942.
cat	LDLo	oral	500mg/kg (500mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: FOOD INTAKE (ANIMAL) GASTROINTESTINAL: NAUSEA OR VOMITING	Journal of Laboratory and Clinical Medicine. Vol. 27, Pg. 1376, 1942.
guinea pig	LD50	intraperitoneal	930mg/kg (930mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ANTIPSYCHOTIC LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 42, Pg. 476, 1953.
mouse	LD50	intraperitoneal	640mg/kg (640mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ANTIPSYCHOTIC LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 42, Pg. 476, 1953.
mouse	LD50	intravenous	400mg/kg (400mg/kg)		Journal of Medicinal Chemistry. Vol. 13, Pg. 997, 1970.
mouse	LD50	oral	2950mg/kg (2950mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ANTIPSYCHOTIC LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 42, Pg. 476, 1953.
rat	LD50	intraperitoneal	510mg/kg (510mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ANTIPSYCHOTIC LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 42, Pg. 476, 1953.
rat	LD50	intravenous	390mg/kg (390mg/kg)	BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Klinische Wochenscrift. Vol. 20, Pg. 125, 1941.
rat	LD50	oral	1100mg/kg (1100mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)	Klinische Wochenscrift. Vol. 20, Pg. 125, 1941.
rat	LD50	subcutaneous	540mg/kg (540mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)	Klinische Wochenscrift. Vol. 20, Pg. 125, 1941.