| dog |
LD50 |
intravenous |
42700ug/kg (42.7mg/kg) |
BEHAVIORAL: ATAXIA
BEHAVIORAL: ANTIPSYCHOTIC
GASTROINTESTINAL: NAUSEA OR VOMITING |
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 244, Pg. 130, 1980. |
| dog |
LD50 |
oral |
> 160mg/kg (160mg/kg) |
? |
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 244, Pg. 130, 1980. |
| dog |
LD50 |
rectal |
> 120mg/kg (120mg/kg) |
? |
Yakkyoku. Pharmacy. Vol. 35, Pg. 625, 1984. |
| dog |
LD50 |
subcutaneous |
> 160mg/kg (160mg/kg) |
? |
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 244, Pg. 130, 1980. |
| guinea pig |
LD50 |
intravenous |
42900ug/kg (42.9mg/kg) |
BEHAVIORAL: ATAXIA
GASTROINTESTINAL: NAUSEA OR VOMITING
BEHAVIORAL: ANTIPSYCHOTIC |
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 244, Pg. 130, 1980. |
| human |
LDLo |
intravenous |
429ug/kg (0.429mg/kg) |
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
British Medical Journal. Vol. 288, Pg. 1728, 1984. |
| human |
TDLo |
intravenous |
714ug/kg (0.714mg/kg) |
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
British Medical Journal. Vol. 288, Pg. 1728, 1984. |
| infant |
TDLo |
oral |
1170ug/kg/1D- (1.17mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE |
Journal of Pediatrics. Vol. 108, Pg. 630, 1986. |
| man |
TDLo |
intramuscular |
200ug/kg (0.2mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE
BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) |
Lancet. Vol. 2, Pg. 1259, 1980. |
| man |
TDLo |
oral |
234mg/kg/39W- (234mg/kg) |
ENDOCRINE: GYNECOMASTIA |
Postgraduate Medical Journal. Vol. 67, Pg. 401, 1991. |
| mouse |
LD50 |
intraperitoneal |
> 8gm/kg (8000mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 3991, 1980. |
| mouse |
LD50 |
intravenous |
46500ug/kg (46.5mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 3991, 1980. |
| mouse |
LD50 |
oral |
> 8gm/kg (8000mg/kg) |
? |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 13, Pg. 1128, 1982. |
| mouse |
LD50 |
subcutaneous |
> 8gm/kg (8000mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 3991, 1980. |
| rat |
LD50 |
intraperitoneal |
61200ug/kg (61.2mg/kg) |
? |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 13, Pg. 1128, 1982. |
| rat |
LD50 |
intravenous |
41700ug/kg (41.7mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 3991, 1980. |
| rat |
LD50 |
oral |
5243mg/kg (5243mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE
BEHAVIORAL: ATAXIA
LUNGS, THORAX, OR RESPIRATION: DYSPNEA |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 3991, 1980. |
| rat |
LD50 |
rectal |
> 250mg/kg (250mg/kg) |
? |
Yakkyoku. Pharmacy. Vol. 35, Pg. 625, 1984. |
| rat |
LD50 |
subcutaneous |
> 8gm/kg (8000mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
LUNGS, THORAX, OR RESPIRATION: CYANOSIS |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 3991, 1980. |
| women |
TDLo |
intravenous |
600ug/kg/1D (0.6mg/kg) |
CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION) |
Lancet. Vol. 2, Pg. 385, 1985. |
| women |
TDLo |
intravenous |
1mg/kg (1mg/kg) |
CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION) |
British Medical Journal. Vol. 289, Pg. 1579, 1984. |
| women |
TDLo |
rectal |
7200ug/kg/30H (7.2mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE |
Journal of Pediatrics. Vol. 105, Pg. 852, 1984.
? |
Xn