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Home > products > (7S-cis)-9-acetyl-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxynaphthacene-5,12-dione hydrochloride

(7S-cis)-9-acetyl-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxynaphthacene-5,12-dione hydrochloride cas no:57852-57-0

Synonyms: Idarubicin Hydrochloride

Identification
Name(7S-cis)-9-acetyl-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxynaphthacene-5,12-dione hydrochloride
CAS57852-57-0
SynonymsIdarubicin Hydrochloride
EINECS(EC#)260-990-7
Molecular FormulaC26H27NO9?HCl
Molecular Weight533.95
Chemical Properties
storage temp2-8°C
Safety Data

Hazard T+:Verytoxic;
Risk R60;R61;R28;R40
Safety

A poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. When heated to decomposition it emits toxic vapors of NOx, HCl, and Cl.
Hazard Codes: VeryT+HarmfulXn
Risk Statements: 60-61-28-40
R28: Very toxic if swallowed. 
R40: Limited evidence of a carcinogenic effect. 
R60: May impair fertility. 
R61: May cause harm to the unborn child.
Safety Statements: 53-45-36-22
S22: Do not breathe dust. 
S36: Wear suitable protective clothing. 
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S53: Avoid exposure - obtain special instructions before use.
RIDADR: UN2811
RTECS: HB7877000


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD intravenous > 500ug/kg (0.5mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 364, 1995.
mouse LD50 intravenous 4100ug/kg (4.1mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 364, 1995.
mouse LD50 oral 13980ug/kg (13.98mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 364, 1995.
mouse LD50 subcutaneous 4690ug/kg (4.69mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 364, 1995.
mouse LDLo intraperitoneal 700ug/kg (0.7mg/kg)   Cancer Treatment Reports. Vol. 60, Pg. 829, 1976.
rat LD50 intravenous 3080ug/kg (3.08mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 364, 1995.
rat LD50 oral 5430ug/kg (5.43mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 364, 1995.
rat LD50 subcutaneous 2930ug/kg (2.93mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 364, 1995.

supplier list

SPE Chemicals Co., Ltd.
Tel:+86-(21)-51386314
Address: 1615 Room, TongHua building, NO.345, Jinxiang Road, Pudong, Shanghai 201206,
Taizhou Creating Chemical Co. ,Ltd.
Tel:+86-(576)-88827176,88820069
Address: B Suite 12F,JiangbinBuilding,Jiaojiang, Taizhou, Zhejiang,
Haorui Pharma-Chem Inc.
Tel:+1-(732)-906-7666
Address: 100 Menlo Park Dr, Suite 316, Edison, New Jersey 08837-242,
Tecoland Corporation
Tel:+1-(732)-603-9577
Address: 100 Menlo Park Drive, Suite 316, Edison, New Jersey 08837-2428,
Kouting Chemical Co.,Ltd
Tel:+86-(21)-58116473
Address: Hunan Road, Pudong New District, Shanghai, Shanghai 201318,
Hangzhou Haichem Co.,Ltd.
Tel:86-571-86024803
Address: 42 Fengqi East Road
lotuschem
Tel:852-29738324
Address: Rm. 907. JCD116 Wing Tuck Commercial Centre, 177-183 Wing Lok Street, Hong Kong
Shanghai Henghe Pharma-Tech
Tel:+86-15862471140
Address: Building C26, No.218 Xinghu Road, Suzhou Industrial Park, Suzhou, Jiangsu, 215011 China
Shanghai Yingxuan Pharmaceutical Science&Technology Co., LTD
Tel:+86-21-60875125
Address: RM431 of BLDG 1,No.2588,Jinhai Road,Pudong New District, Shanghai,CN-201209,China
Taizhou Xinfangxiang Chemical Co., Ltd
Tel:0086-576-88 587168
Address: 0086-576-88 587178
Shanghai Hope Chem Co., Ltd.
Tel:86-21-61723543
Address: Room508, Building1, No.88 CaiLun Road Zhangjiang H
U-Chemo Holding Co.,Limited
Tel:0086-21-61558312
Address: 28C, No.1381, Dong Fang Road, Pudong District, Shanghai, China
AOPHARM
Tel:86-311-66600578
Address: C-2103 Wonder Business Square, 15 Yuhua West Rd.
Hangzhou Dayangchem Co., Ltd.
Tel:86-571-88938639
Address: 9/F Unit 2 ChangdiTorch Building, 259 #WenSan Road
Nanjing Bangnuo Biotechnology Co., Ltd
Tel:86-1732-7098554
Address: shuanglong road,jiangning, nanjing,jiangsu

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