57852-57-0|(7S-cis)-9-acetyl-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxynaphthacene-5,12-dione hydrochlorideProducts Supply

(7S-cis)-9-acetyl-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxynaphthacene-5,12-dione hydrochloride cas no:57852-57-0

Synonyms: Idarubicin Hydrochloride

Identification

Name(7S-cis)-9-acetyl-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxynaphthacene-5,12-dione hydrochloride
CAS57852-57-0
SynonymsIdarubicin Hydrochloride
EINECS(EC#)260-990-7
Molecular FormulaC26H27NO9?HCl
Molecular Weight533.95

Chemical Properties

storage temp2-8°C

Safety Data

Hazard T+:Verytoxic;
Risk R60;R61;R28;R40
Safety

A poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. When heated to decomposition it emits toxic vapors of NO_x, HCl, and Cl⁻.
Hazard Codes: Very T+ Harmful Xn
Risk Statements: 60-61-28-40
R28: Very toxic if swallowed.
R40: Limited evidence of a carcinogenic effect.
R60: May impair fertility.
R61: May cause harm to the unborn child.
Safety Statements: 53-45-36-22
S22: Do not breathe dust.
S36: Wear suitable protective clothing.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S53: Avoid exposure - obtain special instructions before use.
RIDADR: UN2811
RTECS: HB7877000

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
dog	LD	intravenous	> 500ug/kg (0.5mg/kg)	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 364, 1995.
mouse	LD50	intravenous	4100ug/kg (4.1mg/kg)	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 364, 1995.
mouse	LD50	oral	13980ug/kg (13.98mg/kg)	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 364, 1995.
mouse	LD50	subcutaneous	4690ug/kg (4.69mg/kg)	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 364, 1995.
mouse	LDLo	intraperitoneal	700ug/kg (0.7mg/kg)	Cancer Treatment Reports. Vol. 60, Pg. 829, 1976.
rat	LD50	intravenous	3080ug/kg (3.08mg/kg)	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 364, 1995.
rat	LD50	oral	5430ug/kg (5.43mg/kg)	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 364, 1995.
rat	LD50	subcutaneous	2930ug/kg (2.93mg/kg)	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 364, 1995.

supplier list

SPE Chemicals Co., Ltd.: Tel:+86-(21)-51386314; Address: 1615 Room, TongHua building, NO.345, Jinxiang Road, Pudong, Shanghai 201206,

Yingxuan Chempharm Co., Ltd.: Tel:+86-(21)-50323911; Address: Rm.1705, No.51, JinZang Rd., Pudong, Shanghai 201206,

Taizhou Creating Chemical Co. ,Ltd.: Tel:+86-(576)-88827176,88820069; Address: B Suite 12F,JiangbinBuilding,Jiaojiang, Taizhou, Zhejiang,

Hello VetChem Company: Tel:+86-(21)-6688277; Address: Jinshanwei Industrial Park, Shanghai 200011,

Shangai Maxchemco Chemical Industry Limited: Tel:+86-(21)-54822160; Address: No.1305-8, B241, The Ecust Park, Huajing Road, Xuhui, Shanghai,

Kang-Sun Pharmaceutical Limited: Tel:+86-(517)-88842817; Address: Jialv Xiyuan 15-2-602,Xihu District, HangZhou, Zhejiang,

Haorui Pharma-Chem Inc.: Tel:+1-(732)-906-7666; Address: 100 Menlo Park Dr, Suite 316, Edison, New Jersey 08837-242,

Facus Pharmaceutical Co., Ltd.: Tel:+86-(574)-6237-8411; Address: 24Fl, Yuanjing Building, Beilun, Ningbo, Zhejiang 315800,

Shanghai Rainbow Chemistry Co., Ltd.: Tel:+86-(21)-64965859,64968085; Address: Room 128, Building B, No. 8, Lane 1305, Huajing Road, Xuhui Area, Shanghai 200231,

Taizhou Xinfangxiang Chemical Co., Ltd.: Tel:+86-(576)-88587168; Address: Waisha Chemical Industry Zone, Taizhou, Zhejiang 318000,

Taizhou Xingcheng Chempharm Co., Ltd.: Tel:+86-(576)-88886292, 88525005; Address: B Area. 10 Floor.Yaodadasha. 289#.Shifu Road, Taizhou, Zhejiang 318000,

Taizhou Crene Chempharm Co., Ltd.: Tel:+86-(576)-88813233; Address: Weiwu Load Economic Developed Zone, Taizhou, Zhejiang 318000,

Kouting Chemical Co.,Ltd: Tel:+86-(21)-58116473; Address: Hunan Road, Pudong New District, Shanghai, Shanghai 201318,

Greensyn(Guangzhou) Co.,Ltd.: Tel:+86-20-32068825 32068515 13826468465; Address: 11 Baoshi Road, Economic&Technological Development Zone, Guangzhou,China

Haikou Hengkang Chemical Co., Ltd.: Tel:+86-898-31989500; Address: D3-505 Hua Li garden Pobo Road, Haikou570206

(7S-cis)-9-acetyl-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxynaphthacene-5,12-dione hydrochloride cas no:57852-57-0

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