Benzenemethanol,4-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]-,hydrochloride (1:1) cas no:579-56-6

NameBenzenemethanol,4-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]-,hydrochloride (1:1)
CAS579-56-6
SynonymsBenzenemethanol,4-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]-,hydrochloride (9CI); Benzyl alcohol, p-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]-,hydrochloride (8CI); Norephedrine, p-hydroxy-N-(1-methyl-2-phenoxyethyl)-,hydrochloride (6CI); 1-(p-Hydroxyphenyl)-2-(1'-methyl-2'-phenoxy)ethylaminopropanol-1hydrochloride; Dilavase; Divadilan; Duvadilan; Duviculine; Isolait; Isoxsuprinhydrochloride; Isoxsuprine hydrochloride; Navilox; Suprilent; Suprox SR;Vadosilan; Vasodilan; Vasoplex; Vasotran
EINECS(EC#)209-443-6
Molecular FormulaC18H23 N O3 . Cl H
Molecular Weight337.88

Hazard Xn: Harmful;
Risk R22
Safety

Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. An experimental teratogen. Used as a vasodilator. When heated to decomposition it emits toxic fumes of NO_x and HCl. 
Hazard Codes:
Xn
Risk Statements:
R22:Harmful if swallowed.
Safety Statements:
S36:Wear suitable protective clothing.
WGK Germany: 3
RTECS: DO8225000

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	57mg/kg (57mg/kg)	behavioral: ataxia cardiac: change in rate skin and appendages (skin): "dermatitis, other: after systemic exposure"	Toxicology and Applied Pharmacology. Vol. 1, Pg. 579, 1959.
dog	LD50	oral	> 1200mg/kg (1200mg/kg)	gastrointestinal: nausea or vomiting	Toxicology and Applied Pharmacology. Vol. 1, Pg. 579, 1959.
dog	LD50	subcutaneous	143mg/kg (143mg/kg)		Toxicology and Applied Pharmacology. Vol. 1, Pg. 579, 1959.
mouse	LD50	intraperitoneal	185mg/kg (185mg/kg)	behavioral: excitement lungs, thorax, or respiration: respiratory depression gastrointestinal: changes in structure or function of salivary glands	Toxicology and Applied Pharmacology. Vol. 1, Pg. 579, 1959.
mouse	LD50	intravenous	61mg/kg (61mg/kg)	behavioral: excitement gastrointestinal: changes in structure or function of salivary glands lungs, thorax, or respiration: respiratory depression	Toxicology and Applied Pharmacology. Vol. 1, Pg. 579, 1959.
mouse	LD50	oral	1100mg/kg (1100mg/kg)	behavioral: excitement lungs, thorax, or respiration: respiratory depression gastrointestinal: changes in structure or function of salivary glands	Toxicology and Applied Pharmacology. Vol. 1, Pg. 579, 1959.
mouse	LD50	subcutaneous	1500mg/kg (1500mg/kg)	behavioral: excitement lungs, thorax, or respiration: respiratory depression gastrointestinal: changes in structure or function of salivary glands	Toxicology and Applied Pharmacology. Vol. 1, Pg. 579, 1959.
rat	LD50	intraperitoneal	164mg/kg (164mg/kg)		Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971.
rat	LD50	intravenous	77mg/kg (77mg/kg)		Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 9, Pg. 759, 1967.
rat	LD50	oral	1750mg/kg (1750mg/kg)		Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971.