Menadione cas no:58-27-5
Synonyms: 1,4-Naphthalenedione,2-methyl-;2-Methyl-1,4-naphthalenedione;Kipca;VK3;Karcon;Kayklot;Kanone;Kayquinone;Memodol;Menaquinone 0;Kappaxin;Aquakay;2-Methylnaphthoquinone;Menadionum;Klottone;Kappaxin (TN);3-Methyl-1,4-naphthoquinone;K-Thrombyl;2-Methyl-1,4-naphthochinon [German];Synkay;Methyl-1,4-naphthoquinone;Methyl-1,4-naphthalenedione;Usaf ek-5185;Kappaxan (VAN);Mitenone;2-Methyl-1,4-naftochinon [Czech];Prestwick_313;Menadion;2-Methyl-1,4-naphthochinon;Vitamin K3;1,4-Naphthoquinone, 2-methyl-;Juva-K;1,4-Naphthalenedione, 2-methyl-;Riboflavin (Vitamin B2);Kolklot;Vitamin K2 (0);Hemodal;1, 4-Naphthoquinone, 2-methyl-;Koaxin;Menaphthone;Kaykot;Menaphthon;MNQ;Kaergona;2-methyl-1,4-dihydronaphthalene-1,4-dione;
NameMenadione
CAS58-27-5
Synonyms1,4-Naphthalenedione,2-methyl-;2-Methyl-1,4-naphthalenedione;Kipca;VK3;Karcon;Kayklot;Kanone;Kayquinone;Memodol;Menaquinone 0;Kappaxin;Aquakay;2-Methylnaphthoquinone;Menadionum;Klottone;Kappaxin (TN);3-Methyl-1,4-naphthoquinone;K-Thrombyl;2-Methyl-1,4-naphthochinon [German];Synkay;Methyl-1,4-naphthoquinone;Methyl-1,4-naphthalenedione;Usaf ek-5185;Kappaxan (VAN);Mitenone;2-Methyl-1,4-naftochinon [Czech];Prestwick_313;Menadion;2-Methyl-1,4-naphthochinon;Vitamin K3;1,4-Naphthoquinone, 2-methyl-;Juva-K;1,4-Naphthalenedione, 2-methyl-;Riboflavin (Vitamin B2);Kolklot;Vitamin K2 (0);Hemodal;1, 4-Naphthoquinone, 2-methyl-;Koaxin;Menaphthone;Kaykot;Menaphthon;MNQ;Kaergona;2-methyl-1,4-dihydronaphthalene-1,4-dione;
EINECS(EC#)200-372-6
Molecular FormulaC11H8O2
Molecular Weight172.18
AppearanceBright yellow crystals
storage tempStore at RT.
Sensitive Light Sensitive
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
HazardclassIRRITANT
Hazard Xn:Harmful
Risk R22;R36/37/38;R43
Safety
Hazard Codes:?Xn,Xi
Risk Statements: 22-36/37/38-43
R22:Harmful if swallowed.?
R36/37/38:Irritating to eyes, respiratory system and skin.?
R43:May cause sensitization by skin contact.
Safety Statements: 26-36-37/39-24
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36:Wear suitable protective clothing.?
S37/39:Wear suitable gloves and eye/face protection.?
S24:Avoid contact with skin.
WGK Germany: 3
RTECS: QL9100000
F: 8
Poison by ingestion, intraperitoneal, and subcutaneous routes. Experimental teratogenic effects. Questionable carcinogen with experimental tumorigenic data. Human mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| chicken |
LDLo |
intraperitoneal |
100mg/kg (100mg/kg) |
? |
Proceedings of the Society for Experimental Biology and Medicine. Vol. 43, Pg. 125, 1940. |
| mouse |
LD50 |
intraperitoneal |
50mg/kg (50mg/kg) |
? |
National Technical Information Service. Vol. AD691-490, |
| mouse |
LD50 |
oral |
500mg/kg (500mg/kg) |
? |
Proceedings of the Society for Experimental Biology and Medicine. Vol. 43, Pg. 125, 1940. |
| mouse |
LD50 |
subcutaneous |
138mg/kg (138mg/kg) |
? |
Journal of Pharmacology and Experimental Therapeutics. Vol. 75, Pg. 111, 1942. |
| rabbit |
LDLo |
oral |
230mg/kg (230mg/kg) |
VASCULAR: OTHER CHANGES |
Journal of Pharmacology and Experimental Therapeutics. Vol. 75, Pg. 111, 1942. |
| rat |
LD50 |
intraperitoneal |
75mg/kg (75mg/kg) |
? |
Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971. |
