Dypyridamole cas no:58-32-2
Synonyms: Ethanol,2,2',2'',2'''-[(4,8-dipiperidinopyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetra-(6CI,8CI);2,2',2'',2'''-[[4,8-Dipiperidinopyrimido(5,4-d)pyrimidine-2,6-diyl]dinitrilo]tetraethanol;2,6-Bis(diethanolamino)-4,8-dipiperidinopyrimido[5,4-d]pyrimidine;Anginal;Apricor;Cardioflux;Cardoxil;Cardoxin;Cleridium;Coronarine;Corosan;Coroxin;Curantyl;Gulliostin;Kurantil;Peridamol;Persantin;Persantine;Piroan;Prandiol;
NameDypyridamole
CAS58-32-2
SynonymsEthanol,2,2',2'',2'''-[(4,8-dipiperidinopyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetra-(6CI,8CI);2,2',2'',2'''-[[4,8-Dipiperidinopyrimido(5,4-d)pyrimidine-2,6-diyl]dinitrilo]tetraethanol;2,6-Bis(diethanolamino)-4,8-dipiperidinopyrimido[5,4-d]pyrimidine;Anginal;Apricor;Cardioflux;Cardoxil;Cardoxin;Cleridium;Coronarine;Corosan;Coroxin;Curantyl;Gulliostin;Kurantil;Peridamol;Persantin;Persantine;Piroan;Prandiol;
EINECS(EC#)200-374-7
Molecular FormulaC24H40N8O4
Molecular Weight504.6256
AppearanceYellow Powder
refractive index1.666
storage temp?20°C
Hazard Xi:Irritant
Risk R36/37/38
Safety
Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. Human systemic effects cardiomyopathy including infarction. Mutation data reported. Used as a coronary vasodilator. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes:?Xi
Risk Statements:?36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements:?26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36:Wear suitable protective clothing.
WGK Germany: 2
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dni-rat:lvr 200?nmol/L
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CNREA8 ?? Cancer Research. 43 (1983),1616. |
| 2. |
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oms-rat:lvr 300?nmol/L
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CNREA8 ?? Cancer Research. 43 (1983),1616. |
| 3. |
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oms-mus:ast 60 μmol/L
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BCPCA6 ?? Biochemical Pharmacology. 22 (1973),2511. |
| 4. |
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orl-man LDLo:1429?μg/kg:CVS
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JAMAAP ?? JAMA, Journal of the American Medical Association. 257 (1987),1515. |
| 5. |
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orl-man TDLo:1071?μg/kg:CVS
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JAMAAP ?? JAMA, Journal of the American Medical Association. 257 (1987),1515. |
| 6. |
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orl-rat LD50:8400?mg/kg
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MEIEDD ?? Merck Index. 10 (1983),489. |
| 7. |
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scu-rat LD50:1650?mg/kg
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ARZNAD ?? Arzneimittel-Forschung. Drug Research. 22 (1972),892. |
| 8. |
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ivn-rat LD50:195?mg/kg
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ARZNAD ?? Arzneimittel-Forschung. Drug Research. 22 (1972),892. |
| 9. |
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orl-mus LD50:2150?mg/kg
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ARZNAD ?? Arzneimittel-Forschung. Drug Research. 11 (1961),848. |
| 10. |
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ipr-mus LD50:150?mg/kg
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NTIS** ?? National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) AD691-490 . |
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