2H-Benzo[a]quinolizin-2-one,1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-, (3R,11bR)-rel- cas no:58-46-8
Synonyms: 2H-Benzo[a]quinolizin-2-one,1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy- (6CI,8CI);2H-Benzo[a]quinolizin-2-one,1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-, cis-; (?à)-Tetrabenazine; NSC 169886; NSC172187; Ro 1-9569; Rubigen; Tetrabenazine;cis-2-Oxo-3-isobutyl-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-11bH-benzo[a]quinolizine
Name2H-Benzo[a]quinolizin-2-one,1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-, (3R,11bR)-rel-
CAS58-46-8
Synonyms2H-Benzo[a]quinolizin-2-one,1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy- (6CI,8CI);2H-Benzo[a]quinolizin-2-one,1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-, cis-; (?à)-Tetrabenazine; NSC 169886; NSC172187; Ro 1-9569; Rubigen; Tetrabenazine;cis-2-Oxo-3-isobutyl-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-11bH-benzo[a]quinolizine
EINECS(EC#)200-383-6
Molecular FormulaC19H27 N O3
Molecular Weight317.47
Appearancewhite to off-white solid
refractive index1.554
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Hazard Xn: Harmful;
Risk R22
Safety
Poison by subcutaneous and intraperitoneal routes. Moderately toxic by ingestion. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.
Safety Information of Tetrabenazine (CAS NO.58-46-8):
Hazard Codes: Xn.gif)
Risk Statements: 22
22: Harmful if swallowed
| 1. |
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orl-mus LD50:550 mg/kg
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27ZQAG Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,308. |
| 2. |
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ipr-mus LD50:250 mg/kg
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NTIS** National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) AD691-490 . |
| 3. |
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scu-mus LD50:400 mg/kg
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27ZQAG Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,308. |
| 4. |
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ivn-mus LD50:150 mg/kg
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PSCBAY Psychopharmacology Service Center, Bulletin. 2 (1963),17. |
