58-58-2|Adenosine,3'-[[(2S)-2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl-,hydrochloride (1:2)Products Supply

Adenosine,3'-[[(2S)-2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl-,hydrochloride (1:2) cas no:58-58-2

Synonyms: Adenosine,3'-(a-amino-p-methoxyhydrocinnamamido)-3'-deoxy-N,N-dimethyl-,dihydrochloride, L- (8CI); Adenosine,3'-[[(2S)-2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl-,dihydrochloride (9CI); Adenosine,3'-[[2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl-,dihydrochloride, (S)-; 3'-(L-a-Amino-p-methoxyhydrocinnamamido)-3'-deoxy-N,N-dimethyladenosinedihydrochloride; CL 13900 dihydrochloride; CL 16,536; CL 16536; NSC 3055; P 638dihydrochloride; PDH; Puromycin dihydrochloride; Puromycin hydrochloride;Stylomycin dihydrochloride

Identification

NameAdenosine,3'-[[(2S)-2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl-,hydrochloride (1:2)
CAS58-58-2
SynonymsAdenosine,3'-(a-amino-p-methoxyhydrocinnamamido)-3'-deoxy-N,N-dimethyl-,dihydrochloride, L- (8CI); Adenosine,3'-[[(2S)-2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl-,dihydrochloride (9CI); Adenosine,3'-[[2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl-,dihydrochloride, (S)-; 3'-(L-a-Amino-p-methoxyhydrocinnamamido)-3'-deoxy-N,N-dimethyladenosinedihydrochloride; CL 13900 dihydrochloride; CL 16,536; CL 16536; NSC 3055; P 638dihydrochloride; PDH; Puromycin dihydrochloride; Puromycin hydrochloride;Stylomycin dihydrochloride
EINECS(EC#)200-387-8
Molecular FormulaC22H29 N7 O5 . 2 Cl H
Molecular Weight471.50956

Chemical Properties

Appearancewhite powder
storage temp−20°C

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1(b)

Safety Data

Hazard Xn
Risk R22
Safety

Mutation data reported. When heated to decomposition it emits toxic fumes of NO_x and HCl.Safety information of Puromycin dihydrochloride (CAS NO.58-58-2):
Hazard Codes Harmful Xn
Risk Statements
22 Harmful if swallowed
40 Limited evidence of a carcinogenic effect
RIDADR 3249
WGK Germany 3
RTECS AU7355000
F 3-8-10
HazardClass 6.1(b)
PackingGroup III

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LD50	intramuscular	202mg/kg (202mg/kg)		Antibiotics Annual. Vol. 2, Pg. 757, 1954/1955.
guinea pig	LD50	intramuscular	202mg/kg (202mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS	Antibiotics Annual. Vol. 2, Pg. 757, 1954/1955.
guinea pig	LD50	intraperitoneal	287mg/kg (287mg/kg)		Antibiotics Annual. Vol. 2, Pg. 757, 1954/1955.
guinea pig	LD50	intraperitoneal	287mg/kg (287mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS	Antibiotics Annual. Vol. 2, Pg. 757, 1954/1955.
guinea pig	LD50	oral	600mg/kg (600mg/kg)		Antibiotics Annual. Vol. 2, Pg. 757, 1954/1955.
guinea pig	LD50	oral	600mg/kg (600mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS	Antibiotics Annual. Vol. 2, Pg. 757, 1954/1955.
mouse	LD50	intraperitoneal	580mg/kg (580mg/kg)		Antibiotics Annual. Vol. 2, Pg. 757, 1954/1955.
mouse	LD50	intraperitoneal	580mg/kg (580mg/kg)	LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Antibiotics Annual. Vol. 2, Pg. 757, 1954/1955.
mouse	LD50	intravenous	335mg/kg (335mg/kg)		Antibiotics Annual. Vol. 2, Pg. 757, 1954/1955.
mouse	LD50	intravenous	335mg/kg (335mg/kg)	LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Antibiotics Annual. Vol. 2, Pg. 757, 1954/1955.
mouse	LD50	oral	720mg/kg (720mg/kg)		Antibiotics Annual. Vol. 2, Pg. 757, 1954/1955.
mouse	LD50	oral	720mg/kg (720mg/kg)	LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Antibiotics Annual. Vol. 2, Pg. 757, 1954/1955.

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Adenosine,3'-[[(2S)-2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl-,hydrochloride (1:2) cas no:58-58-2

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