Dibenzo[b,f][1,4]thiazepine,2-methyl-11-(4-methyl-1-piperazinyl)- cas no:5800-19-1

NameDibenzo[b,f][1,4]thiazepine,2-methyl-11-(4-methyl-1-piperazinyl)-
CAS5800-19-1
Synonyms2-Methyl-11-(4-methyl-1-piperazinyl)-dibenzo[b,f][1,4]thiazepine;Metiapine
Molecular FormulaC19H21 N3 S
Molecular Weight323.49

refractive index1.669

Safety

Poison by intraperitoneal route. Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of NO_x and SO_x.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	320mg/kg (320mg/kg)	BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Toxicology and Applied Pharmacology. Vol. 25, Pg. 220, 1973.
mouse	LD50	oral	680mg/kg (680mg/kg)		Toxicology and Applied Pharmacology. Vol. 22, Pg. 334, 1972.
rat	LD50	intraperitoneal	487mg/kg (487mg/kg)	BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Toxicology and Applied Pharmacology. Vol. 25, Pg. 220, 1973.
rat	LD50	oral	934mg/kg (934mg/kg)		Toxicology and Applied Pharmacology. Vol. 22, Pg. 334, 1972.