Idebenone cas no:58186-27-9
Synonyms: 2,5-Cyclohexadiene-1,4-dione,2-(10-hydroxydecyl)- 5,6-dimethoxy-3-methyl-;Idebenone (JAN);2,5-Cyclohexadiene-1,4-dione, 5,6-dimethoxy-2-(10-hydroxydecyl)-3-methyl-;6-(10-Hydroxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone;CV 2619;Idebenone [GMP];2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-p-benzoquinone;Idebenonum [Latin];Idebenone [INN:JAN];Idebenona [GMP];Idebenona [Spanish];2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-cyclohexa-2,5-diene-1,4-dione;Idenbenone;
NameIdebenone
CAS58186-27-9
Synonyms2,5-Cyclohexadiene-1,4-dione,2-(10-hydroxydecyl)- 5,6-dimethoxy-3-methyl-;Idebenone (JAN);2,5-Cyclohexadiene-1,4-dione, 5,6-dimethoxy-2-(10-hydroxydecyl)-3-methyl-;6-(10-Hydroxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone;CV 2619;Idebenone [GMP];2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-p-benzoquinone;Idebenonum [Latin];Idebenone [INN:JAN];Idebenona [GMP];Idebenona [Spanish];2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-cyclohexa-2,5-diene-1,4-dione;Idenbenone;
Molecular FormulaC19H30O5
Molecular Weight338.44
AppearanceYellow-orange crystalline powder
refractive index1.502
storage tempRoom temp
Hazard Xi: Irritant;
Risk Xi
Safety
Although studies in animals have shown no harmful effects, this product should not be taken during the first three months of pregnancy and during nursing, only when absolutely necessary and always under a doctor's supervision.
Hazard Codes:?
Xi
RTECS: GU5290000
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mammal (species unspecified) |
LD50 |
unreported |
> 1gm/kg (1000mg/kg) |
? |
Chemical and Pharmaceutical Bulletin. Vol. 39, Pg. 367, 1991.
? |
| mouse |
LD50 |
intraperitoneal |
757mg/kg (757mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13, Pg. 3931, 1985. |
| mouse |
LD50 |
oral |
> 10gm/kg (10000mg/kg) |
? |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13, Pg. 3931, 1985. |
| mouse |
LD50 |
subcutaneous |
> 10gm/kg (10000mg/kg) |
? |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13, Pg. 3931, 1985. |
| rat |
LD50 |
intraperitoneal |
830mg/kg (830mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13, Pg. 3931, 1985. |
| rat |
LD50 |
oral |
10gm/kg (10000mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13, Pg. 3931, 1985. |
| rat |
LD50 |
subcutaneous |
> 10gm/kg (10000mg/kg) |
? |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 13, Pg. 3931, 1985. |
