CEPHAELINE HYDROCHLORIDE cas no:5853-29-2

NameCEPHAELINE HYDROCHLORIDE
CAS5853-29-2
SynonymsCephaeline hydrochloride;(-)-Cephaeline dihydrochloride;7',10,11-Trimethoxyemetan-6'-ol dihydrochloride;CEPHAELINE HCL;Cephaleine hydrochloride;NSC 32944;Cephaeline, dihydrochloride (8CI);Emetan-6'-ol, 7',10,11-trimethoxy-, dihydrochloride (9CI);7',10,11-trimethoxyemetan-6'-ol;(2xi,14xi)-6'-hydroxy-7',10,11-trimethoxyemetan-2',5-diium dichloride;ethyl (2Z)-2-{[3-(4-chlorophenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-7-methyl-3-oxo-5-[(E)-2-phenylethenyl]-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
EINECS(EC#)227-463-3
Molecular FormulaC₂₈H₃₈N₂O₄•2ClH
Molecular Weight539.60

refractive index1.672

Safety

Poison by ingestion and intraperitoneal routes. When Cephaeline hydrochloride (CAS NO.5853-29-2) is heated to decomposition, it emits toxic fumes of NO_x and HCl.

RIDADR 1544
HazardClass 6.1(b)
PackingGroup III

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LDLo	subcutaneous	8mg/kg (8mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 10, Pg. 73, 1917/1918.
mouse	LD50	intraperitoneal	20530ug/kg (20.53mg/kg)		National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986,
mouse	LD50	oral	74970ug/kg (74.97mg/kg)		National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986,
rat	LD50	intraperitoneal	10mg/kg (10mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 104, Pg. 421, 1952.
rat	LDLo	subcutaneous	6500ug/kg (6.5mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 10, Pg. 73, 1917/1918.