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19-Norpregna-4,6-diene-3,20-dione,17-(acetyloxy)-6-methyl- cas no:58652-20-3

Synonyms: 6-Methyl-17a-acetoxy-D6-19-norprogesterone;Lutenyl;Nomegestrol acetate;Org 10486-0;Surplant;TX 066;Uniplant;Nomegestrol 17-acetate;

Identification
Name19-Norpregna-4,6-diene-3,20-dione,17-(acetyloxy)-6-methyl-
CAS58652-20-3
Synonyms6-Methyl-17a-acetoxy-D6-19-norprogesterone;Lutenyl;Nomegestrol acetate;Org 10486-0;Surplant;TX 066;Uniplant;Nomegestrol 17-acetate;
EINECS(EC#)261-379-8
Molecular FormulaC23H30O4
Molecular Weight370.49
Chemical Properties
refractive index1.554
Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal > 2gm/kg (2000mg/kg)   Drugs of the Future. Vol. 9, Pg. 657, 1984.
mouse LD50 oral > 2gm/kg (2000mg/kg)   Drugs of the Future. Vol. 9, Pg. 657, 1984.
rat LD50 intraperitoneal > 2gm/kg (2000mg/kg)   Drugs of the Future. Vol. 9, Pg. 657, 1984.
rat LD50 oral > 2gm/kg (2000mg/kg)   Drugs of the Future. Vol. 9, Pg. 657, 1984.
women TDLo oral 1050ug/kg/21D (1.05mg/kg) ENDOCRINE: CHANGE IN LH

ENDOCRINE: ESTROGENIC

ENDOCRINE: EFFECT ON MENSTRUAL CYSLE
British Journal of Obstetrics and Gynaecology. Vol. 94, Pg. 1199, 1987.

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