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Benzeneacetic acid, a-(1-hydroxycyclopentyl)-,2-(dimethylamino)ethyl ester, hydrochloride (1:1) cas no:5870-29-1

Synonyms: Benzeneaceticacid, a-(1-hydroxycyclopentyl)-,2-(dimethylamino)ethyl ester, hydrochloride (9CI); Cyclopentaneacetic acid,1-hydroxy-a-phenyl-, 2-(dimethylamino)ethylester hydrochloride (8CI); (?à)-Cyclopentolate-hydrochloride; 2-(Dimethylamino)ethyl 1-hydroxy-a-phenylcyclopentaneacetatehydrochloride; Ak-Pentolate; Alnide; Cyclopentolate hydrochloride; Cyplegin;Mydplegic; Mydrilate; Zyklolat; b-Dimethylaminoethyl (1-hydroxycyclopentyl)phenylacetate hydrochloride

Identification
NameBenzeneacetic acid, a-(1-hydroxycyclopentyl)-,2-(dimethylamino)ethyl ester, hydrochloride (1:1)
CAS5870-29-1
SynonymsBenzeneaceticacid, a-(1-hydroxycyclopentyl)-,2-(dimethylamino)ethyl ester, hydrochloride (9CI); Cyclopentaneacetic acid,1-hydroxy-a-phenyl-, 2-(dimethylamino)ethylester hydrochloride (8CI); (?à)-Cyclopentolate-hydrochloride; 2-(Dimethylamino)ethyl 1-hydroxy-a-phenylcyclopentaneacetatehydrochloride; Ak-Pentolate; Alnide; Cyclopentolate hydrochloride; Cyplegin;Mydplegic; Mydrilate; Zyklolat; b-Dimethylaminoethyl (1-hydroxycyclopentyl)phenylacetate hydrochloride
EINECS(EC#)227-521-8
Molecular FormulaC17H25 N O3 . Cl H
Molecular Weight327.89
Chemical Properties
storage temp−20°C
Safety Data

Safety

Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. Human systemic effects: convulsions, distorted perceptions, hallucinations, toxic psychosis. When heated to decomposition it emits toxic fumes of NOx and HCl. See also ESTERS.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
child TDLo ocular 50ug/kg/I (0.05mg/kg) BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"

BEHAVIORAL: TOXIC PSYCHOSIS
American Journal of Ophthalmology. Vol. 105, Pg. 91, 1988.
child TDLo subcutaneous 40ug/kg (0.04mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Archives of Ophthalmology Vol. 87, Pg. 634, 1972.
mouse LD50 intraperitoneal 314mg/kg (314mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 106, Pg. 141, 1952.
mouse LD50 intravenous 63mg/kg (63mg/kg)   Drugs in Japan Vol. -, Pg. 516, 1995.
mouse LD50 oral 960mg/kg (960mg/kg)   Drugs in Japan Vol. 6, Pg. 314, 1982.
mouse LD50 subcutaneous 292mg/kg (292mg/kg)   Drugs in Japan Vol. -, Pg. 444, 1990.
rat LD50 oral > 4gm/kg (4000mg/kg)   Drugs in Japan Vol. 6, Pg. 314, 1982.
rat LD50 subcutaneous 2235mg/kg (2235mg/kg)   Drugs in Japan Vol. -, Pg. 444, 1990.

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