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Orciprenaline sulfate cas no:5874-97-5

Synonyms: 3,5-Dihydroxy-alpha-((isopropylamino)methyl)-benzyl alcohol sulfate (2:1); Metaproterenol hemisulfate; Alupent

Identification
NameOrciprenaline sulfate
CAS5874-97-5
Synonyms3,5-Dihydroxy-alpha-((isopropylamino)methyl)-benzyl alcohol sulfate (2:1); Metaproterenol hemisulfate; Alupent
EINECS(EC#)227-539-6
Molecular Formula2(C11H17NO3).H2SO4
Molecular Weight520.66
Safety Data

Hazard Xn
Risk 20
Safety

The Hazard Codes of Metaproterenol sulfate (CAS NO.5874-97-5): HarmfulXn
Risk Statements:R20:Harmful by inhalation. 
Safety Statements:S36:Wear suitable protective clothing. 
Poison by subcutaneous and intravenous routes. Moderately toxic by intraduodenal route. Mildly toxic by ingestion. An experimental teratogen. When heated to decomposition it emits toxic fumes of NOx and SOx. See also SULFATES.


Toxicity

The toxicity of Metaproterenol sulfate (CAS NO.5874-97-5): 

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 114mg/kg (114mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE

LUNGS, THORAX, OR RESPIRATION: CYANOSIS

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 521, 1961.
mouse LD50 oral 4800mg/kg (4800mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE

LUNGS, THORAX, OR RESPIRATION: CYANOSIS

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 521, 1961.
mouse LD50 subcutaneous 290mg/kg (290mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE

LUNGS, THORAX, OR RESPIRATION: CYANOSIS

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 521, 1961.
rat LD50 intraduodenal 2230mg/kg (2230mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 180, Pg. 155, 1969.
rat LD50 oral 5538mg/kg (5538mg/kg)   Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971.
rat LD50 subcutaneous > 4gm/kg (4000mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 180, Pg. 155, 1969.

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