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Toosendanin cas no:58812-37-6

Synonyms: 24-Norchola-20,22-diene-4-carboxaldehyde, 3,12-bis(acetyloxy)-14,15:21,23-diepoxy-1,7,19-trihydroxy-4,8-dimethyl-11-oxo-, cyclic 4,19-hemiacetal, (1-α,3-α,4-β(R), 5-α,7-α,12-α,13-α,14-β,15-β,17-α)-;28-Deacetylsendanin;Chuanliansu;

Identification
NameToosendanin
CAS58812-37-6
Synonyms24-Norchola-20,22-diene-4-carboxaldehyde, 3,12-bis(acetyloxy)-14,15:21,23-diepoxy-1,7,19-trihydroxy-4,8-dimethyl-11-oxo-, cyclic 4,19-hemiacetal, (1-α,3-α,4-β(R), 5-α,7-α,12-α,13-α,14-β,15-β,17-α)-;28-Deacetylsendanin;Chuanliansu;
Molecular FormulaC30H38O11
Molecular Weight574.68
Chemical Properties
AppearanceWhite crystalline powder
refractive index1.618
Safety Data

Safety

Poison by ingestion, subcutaneous, intravenous and intraperitoneal routes. When heated to decomposition it emits acrid smoke and fumes.


Toxicity
Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 13800ug/kg (13.8mg/kg)   Zhongcaoyao. Chinese Traditional and Herbal Medicine. Vol. 13, Pg. 317, 1982.
mouse LD50 intravenous 14600ug/kg (14.6mg/kg)   Zhongcaoyao. Chinese Traditional and Herbal Medicine. Vol. 13, Pg. 317, 1982.
mouse LD50 oral 244mg/kg (244mg/kg)   Zhongcaoyao. Chinese Traditional and Herbal Medicine. Vol. 13, Pg. 317, 1982.
mouse LD50 subcutaneous 14300ug/kg (14.3mg/kg)   Zhongcaoyao. Chinese Traditional and Herbal Medicine. Vol. 13, Pg. 317, 1982.
rabbit LD50 intravenous 4200ug/kg (4.2mg/kg)   Zhongcaoyao. Chinese Traditional and Herbal Medicine. Vol. 13, Pg. 317, 1982.
rat LD50 intraperitoneal 98mg/kg (98mg/kg)   Zhongcaoyao. Chinese Traditional and Herbal Medicine. Vol. 13, Pg. 317, 1982.

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