58957-92-9|5,12-Naphthacenedione,9-acetyl-7-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-,(7S,9S)-Products Supply

5,12-Naphthacenedione,9-acetyl-7-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-,(7S,9S)- cas no:58957-92-9

Synonyms: 5,12-Naphthacenedione,9-acetyl-7-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-,(7S-cis)-;1-Demethoxydaunorubicin;4-DMD;4-Demethoxydaunomycin;4-Demethoxydaunorubicin;Demethoxydaunorubicin;

Identification

Name5,12-Naphthacenedione,9-acetyl-7-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-,(7S,9S)-
CAS58957-92-9
Synonyms5,12-Naphthacenedione,9-acetyl-7-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-,(7S-cis)-;1-Demethoxydaunorubicin;4-DMD;4-Demethoxydaunomycin;4-Demethoxydaunorubicin;Demethoxydaunorubicin;
Molecular FormulaC₂₆H₂₇NO₉
Molecular Weight497.49

Chemical Properties

storage temp2-8°C

Safety Data

Hazard T+
Risk R60
Safety

Poison by ingestion, intraperitoneal, and intravenous routes. Mutation data reported. When heated to decomposition it emits toxic fumes of NO_x. See also DAUNOMYCIN.
Safety information of Idarubicin (58957-92-9):
Hazard Codes T+
Risk Statements
60 May impair fertility
61 May cause harm to the unborn child
28 Very Toxic if swallowed
40 Limited evidence of a carcinogenic effect
Safety Statements
53 Avoid exposure - obtain special instruction before use
45 In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
RIDADR UN 2811 6.1/PG 2
WGK Germany 3
RTECS HB7877000

Toxicity

1.	mmo-sat 2 µg/plate	ENMUDM Environmental Mutagenesis. 7 (1985),129.
2.	dns-rat:lvr 2 mg/L	CNREA8 Cancer Research. 44 (1984),5599.
3.	dnd-mus:fbr 1800 nmol/L	CNREA8 Cancer Research. 37 (1977),4523.
4.	dnd-mam:lym 200 nmol/L	BBRCA9 Biochemical and Biophysical Research Communications. 69 (1976),744.
5.	orl-mus LD50:16 mg/kg	CTRRDO Cancer Treatment Reports. 61 (1977),893.
6.	ipr-mus LD50:3 mg/kg	CNREA8 Cancer Research. 48 (1988),926.
7.	ivn-mus LD50:4 mg/kg	CTRRDO Cancer Treatment Reports. 61 (1977),893.

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5,12-Naphthacenedione,9-acetyl-7-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-,(7S,9S)- cas no:58957-92-9

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