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Home > products > 5,12-Naphthacenedione,9-acetyl-7-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-,(7S,9S)-

5,12-Naphthacenedione,9-acetyl-7-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-,(7S,9S)- cas no:58957-92-9

Synonyms: 5,12-Naphthacenedione,9-acetyl-7-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-,(7S-cis)-;1-Demethoxydaunorubicin;4-DMD;4-Demethoxydaunomycin;4-Demethoxydaunorubicin;Demethoxydaunorubicin;

Identification
Name5,12-Naphthacenedione,9-acetyl-7-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-,(7S,9S)-
CAS58957-92-9
Synonyms5,12-Naphthacenedione,9-acetyl-7-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-,(7S-cis)-;1-Demethoxydaunorubicin;4-DMD;4-Demethoxydaunomycin;4-Demethoxydaunorubicin;Demethoxydaunorubicin;
Molecular FormulaC26H27NO9
Molecular Weight497.49
Chemical Properties
storage temp2-8°C
Safety Data

Hazard T+
Risk R60
Safety

Poison by ingestion, intraperitoneal, and intravenous routes. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also DAUNOMYCIN.
Safety information of Idarubicin (58957-92-9):
Hazard Codes  T+
Risk Statements 
60  May impair fertility
61  May cause harm to the unborn child
28  Very Toxic if swallowed
40  Limited evidence of a carcinogenic effect
Safety Statements 
53  Avoid exposure - obtain special instruction before use
45  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
RIDADR  UN 2811 6.1/PG 2
WGK Germany  3
RTECS  HB7877000


Toxicity
1.    

mmo-sat 2 µg/plate

    ENMUDM    Environmental Mutagenesis. 7 (1985),129.
2.    

dns-rat:lvr 2 mg/L

    CNREA8    Cancer Research. 44 (1984),5599.
3.    

dnd-mus:fbr 1800 nmol/L

    CNREA8    Cancer Research. 37 (1977),4523.
4.    

dnd-mam:lym 200 nmol/L

    BBRCA9    Biochemical and Biophysical Research Communications. 69 (1976),744.
5.    

orl-mus LD50:16 mg/kg

    CTRRDO    Cancer Treatment Reports. 61 (1977),893.
6.    

ipr-mus LD50:3 mg/kg

    CNREA8    Cancer Research. 48 (1988),926.
7.    

ivn-mus LD50:4 mg/kg

    CTRRDO    Cancer Treatment Reports. 61 (1977),893.

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Tel:18918206905
Address: shanghai
ZHONGBEI NORTHLAND BIO-CHEM INDUSTRY CO., LTD.
Tel:+86-452-6197139
Address: SONGLING DISTRICT, JIAGEDAQI CITY, DAXINGANLING, HEILONGJIANG PROVINCE, CHINA
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Address: Beijing TongZhou District
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Tel:+86-(510)-86106900
Address: No.205,zhencheng Road, HI-TECT District, Wuxi, Jiangsu,

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