5,12-Naphthacenedione,9-acetyl-7-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-,(7S,9S)- cas no:58957-92-9
Synonyms: 5,12-Naphthacenedione,9-acetyl-7-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-,(7S-cis)-;1-Demethoxydaunorubicin;4-DMD;4-Demethoxydaunomycin;4-Demethoxydaunorubicin;Demethoxydaunorubicin;
Name5,12-Naphthacenedione,9-acetyl-7-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-,(7S,9S)-
CAS58957-92-9
Synonyms5,12-Naphthacenedione,9-acetyl-7-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-,(7S-cis)-;1-Demethoxydaunorubicin;4-DMD;4-Demethoxydaunomycin;4-Demethoxydaunorubicin;Demethoxydaunorubicin;
Molecular FormulaC26H27NO9
Molecular Weight497.49
storage temp2-8°C
Hazard T+
Risk R60
Safety
Poison by ingestion, intraperitoneal, and intravenous routes. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also DAUNOMYCIN.
Safety information of Idarubicin (58957-92-9):
Hazard Codes .gif)
T+
Risk Statements
60 May impair fertility
61 May cause harm to the unborn child
28 Very Toxic if swallowed
40 Limited evidence of a carcinogenic effect
Safety Statements
53 Avoid exposure - obtain special instruction before use
45 In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
RIDADR UN 2811 6.1/PG 2
WGK Germany 3
RTECS HB7877000
| 1. |
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mmo-sat 2 µg/plate
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ENMUDM Environmental Mutagenesis. 7 (1985),129. |
| 2. |
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dns-rat:lvr 2 mg/L
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CNREA8 Cancer Research. 44 (1984),5599. |
| 3. |
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dnd-mus:fbr 1800 nmol/L
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| 4. |
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dnd-mam:lym 200 nmol/L
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BBRCA9 Biochemical and Biophysical Research Communications. 69 (1976),744. |
| 5. |
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orl-mus LD50:16 mg/kg
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CTRRDO Cancer Treatment Reports. 61 (1977),893. |
| 6. |
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ipr-mus LD50:3 mg/kg
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CNREA8 Cancer Research. 48 (1988),926. |
| 7. |
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ivn-mus LD50:4 mg/kg
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CTRRDO Cancer Treatment Reports. 61 (1977),893. |
