59-26-7|TocainideProducts Supply - Chemical intermediates Network

Tocainide cas no:59-26-7

Synonyms: anacardone; astrocar; inicardio; kardiamid; leptamin; mediamid; niamine; nicamide; nicetamide; nicethamid; Nicor; nicotinic acid diethyl amide; nikethamide; nikotin; N,N-diethyl-3-pyridinecarboxamide; N,N-Diethylnicotinamide; percoral; procardine; pyridine-3-carboxyldiethylamide; pyridine-3-carboxylic acid diethylamide; reformin; salvacord; stellamine; stimulin; Tonocard; vasozol; diethyl-nicotamide; dietilamide-carbopiridina; dinacoryl; betapyrimidum; camphozone; cardiamid; cardiamine; cardamine; citocor; coracon; coraethamidum; coramine; corazone; cordiamin; cordynil; corediol; coretone; cormid; cornotone; corvitan; corvotone; danamine; elitone; hansacor

Identification

NameTocainide
CAS59-26-7
Synonymsanacardone; astrocar; inicardio; kardiamid; leptamin; mediamid; niamine; nicamide; nicetamide; nicethamid; Nicor; nicotinic acid diethyl amide; nikethamide; nikotin; N,N-diethyl-3-pyridinecarboxamide; N,N-Diethylnicotinamide; percoral; procardine; pyridine-3-carboxyldiethylamide; pyridine-3-carboxylic acid diethylamide; reformin; salvacord; stellamine; stimulin; Tonocard; vasozol; diethyl-nicotamide; dietilamide-carbopiridina; dinacoryl; betapyrimidum; camphozone; cardiamid; cardiamine; cardamine; citocor; coracon; coraethamidum; coramine; corazone; cordiamin; cordynil; corediol; coretone; cormid; cornotone; corvitan; corvotone; danamine; elitone; hansacor
EINECS(EC#)200-418-5
Molecular FormulaC10H14N2O
Molecular Weight178.2334

Chemical Properties

refractive indexn20/D 1.524(lit.)

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1(b)

Safety Data

Hazard T:Toxic;
Risk R23/24/25
Safety

Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. When heated to decomposition it emits toxic fumes of NO_x.
Hazard Codes:
T: Toxic
Risk Statements:
R25: Toxic if swallowed.
R36/37/38: Irritating to eyes, respiratory system and skin.
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed.
Safety Statements:
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: QS4375000
HazardClass: 6.1(b)
PackingGroup: III

Toxicity

1.	ipr-rat LD50:272 mg/kg	PSDTAP Proceedings of the European Society for the Study of Drug Toxicity. 4 (1964),132.
2.	scu-rat LD50:240 mg/kg	PSEBAA Proceedings of the Society for Experimental Biology and Medicine. 62 (1946),19.
3.	ivn-rat LD50:191 mg/kg	27ZIAQ Drug Dosages in Laboratory Animals-A Handbook C.D. Barnes andL.G. Eltherington,Berkeley, CA.: Univ. of California Press,1973,173.
4.	orl-mus LD50:188 mg/kg	RPOBAR Research Progress in Organic Biological and Medicinal Chemistry. 1 (1964),423.
5.	ipr-mus LD50:174 mg/kg	JPETAB Journal of Pharmacology and Experimental Therapeutics. 128 (1960),176.
6.	scu-mus LD50:200 mg/kg	BCFAAI Bollettino Chimico Farmaceutico. 111 (1972),293.
7.	ivn-mus LD50:180 mg/kg	SMWOAS Schweizerische Medizinische Wochenschrift. 85 (1955),305.
8.	scu-dog LDLo:175 mg/kg	27ZWAY Heffters Handbuch der Experimentelle Pharmakologie .1937.
9.	ivn-dog LDLo:175 mg/kg	27ZWAY Heffters Handbuch der Experimentelle Pharmakologie .1937.
10.	ipr-rbt LD50:225 mg/kg

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Tocainide cas no:59-26-7

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